Enzyme or protein defect
ALA dehydratase and ferrochelatase
Accumulates or becomes deficient
ALA, protoporphyrin (zinc protoporphyrin)
Key features
Microcytic anaemia with basophilic stippling, abdominal colic, wrist/foot drop, encephalopathy, gingival lead lines
Management
Chelation (succimer, EDTA, dimercaprol)
Not clinical guidance. Written from standard clinical biochemistry, not from the uploaded documents, and marked unreviewed. Teaching-level reference for study and database seeding only. It must not be used to manage a patient.
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Exogenous pipecolic acid ameliorates lead-induced phytotoxicity in chili (<i>Capsicum annuum</i> L.) by enhancing antioxidant capacity and physiological homeostasis.
Iqbal R, Mehmood H, Majeed A, Murtaza G, Huseynova A, Ullah S, Ditta A, Aldahmash B, Rady A. · 2026-06-01
cited 1× open access unreviewed -
2
Microalgae as novel drug-delivery system for biomedical field.
Dai Y, Guo D, Li A, Chen W, Yang Y, Li S, Yang L, Feng S. · 2026-01-27
open access unreviewed -
3
Advances in the clinical applications of sodium thiosulphate.
Deng Y, Ke J, Zang H, Liu Y, Wang P. · 2026-01-05
cited 1× open access unreviewed -
4
Environmental Burden of Lead and Public Health Issues in Nigeria: A Systematic Review of Emerging Evidence.
Madaki PD, Frazzoli C, Ibibama JO, Tengbeh AS, Orisakwe OE. · 2026-06-15
unreviewed -
5
Occupational Exposure to Lead Increases Inflammation that Causes Cardiovascular Disease and Lowers Selenium levels.
Kadam NJ, Awad NAN, Al-Taher SSH. · 2024-11-18
unreviewed -
6
Blood Lead Testing Among Children Enrolled in Medicaid.
Cornwell CR, Pennington AF, Williams T, Ruckart PZ, Courtney JG, Allwood P. · 2026-08-01
unreviewed -
7
Sociodemographic and maternal predictors of elevated blood lead levels during pregnancy in Adjara, Georgia.
Sikharulidze S, Rylander C, Caudle WM, Shavishvili R, Ephadze N, Gvelesiani T, Manjavidze T. · 2026-06-16
open access unreviewed -
8
Lead exposure and poisoning among artisanal kohl manufacturers in Fez, Morocco.
Achour S, Iken I, Chellal W, Metarfi Y, Ben Khadda Z, Hoummani H, Abidi K, Messouak O, Belahsen F, Dumont X, … · 2026-06-01
unreviewed -
9
[Analysis of blood lead level and its influencing factors in lead workers based on active monitoring].
Wang X, Gao Y, Bai Y, Wang XG, Li P, Zeng Q. · 2026-07-01
unreviewed -
10
Systemic Lead Poisoning Secondary to Retained Intra-articular Bullet: A Case Report.
Dunwody D, Lambert J, Register A, Martell M, Padget W. · 2026-07-30
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.