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unreviewed

Choline acetyltransferase (ChAT)

1 reactions · 1 pathways

Cofactors used

Acetyl-CoA

Clinical / pharmacological. Acetylcholine synthesis; AChE is the organophosphate target

What it does, reaction by reaction

1 reactions

Other Neurotransmitter Synthesis Amino Acid & Nitrogen Metabolism · Cytosol

step 3 Irreversible/directional

Choline + acetyl-CoA -> acetylcholine + CoA-SH

Converts Choline Acetyl-CoA into Acetylcholine CoA-SH

› Notes

Hydrolysed at the synapse by acetylcholinesterase, the target of organophosphates and of anticholinesterase drugs.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    Use of Artificial Intelligence in obtaining canine diets: nutritional inadequacy and the need for technical knowledge.

    Rosa MBS, França J, Siqueira MTS, Raineri C. · 2026-07-20

    unreviewed
  2. 2
    INTERPOL Review of Forensic Biology and DNA, 2023-2025.

    Butler JM. · 2026-06-14

    open access unreviewed
  3. 3
    Interpol review of forensic science management, 2022-2025.

    McAndrew WP, Speaker PJ. · 2026-06-12

    open access unreviewed
  4. 4
    Digital clinic users in Finnish public primary care: their characteristics, reasons for visits, and equity considerations - a register study.

    Kujansivu K, Tolvanen E, Haaga T, Sääksvuori L, Kortelainen M, Nokso-Koivisto O, Koskela TH. · 2026-06-18

    open access unreviewed
  5. 5
    Intratumor <i>Lactobacillus</i> drives ferroptosis resistance via D-lactate-STAT3 K631 lactylation in esophageal squamous cell carcinoma.

    Wang D, Lu H, Li W, Li L, Xu X, Zhou H, Tao H, Li Y, Wei W, Wu K, Wang Y, Li R, Li Y, Yao W, Chen Y, Wang F, … · 2026-06-11

    open access unreviewed
  6. 6
    Postharvest preservation of fruits and vegetables by light-emitting diodes.

    Vijeev A, Basha S, S Nadig S, Mahato KK. · 2026-06-09

    open access unreviewed
  7. 7
    'Wala kaming alam sa stroke care' (we don't know anything about stroke care): experiences of care providers delivering stroke rehabilitation care in the Philippines.

    Leggat F, Buckingham SA, Ong APR, Kent B, Santos NM, Teves A, Boac V, Valera PM, Anota E, Barba MM, Estrada M… · 2026-06-05

    open access unreviewed
  8. 8
    "Who I am": understanding the self-identity process of autism in adults in the UK.

    Overton GL, Marsà-Sambola F, Martin R, Cavenagh P. · 2026-06-02

    open access unreviewed
  9. 9
    Oxidative stress biomarkers and flavonoids in Alzheimer's disease: current clinical evidence and therapeutic perspectives.

    Zainuddin MS, Pamidi N, Azman AS, Bai Magalingam K, Bhuvanendran S. · 2026-05-26

    open access unreviewed
  10. 10
    Factors affecting nurses' acceptance of a digital triage platform in primary health care in Sweden: an extended UTAUT analysis.

    Hermansson-Borrebaeck R, Milos-Nymberg V, Glock H, Jakobsson U, Midlöv P, Calling S. · 2026-05-25

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.