Carnitine-acylcarnitine translocase (CACT)
Cofactors used
What it does, reaction by reaction
Beta-Oxidation of Fatty Acids Lipid Metabolism · Mitochondrial matrix (peroxisome for VLCFA)
Acylcarnitine (cytosolic side) → acylcarnitine (matrix side)
Converts Acylcarnitine into Acylcarnitine
› Notes
The inner-membrane carnitine–acylcarnitine translocase (CACT) exchanges incoming acylcarnitine for free carnitine moving outward. No ATP is directly consumed.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Altered Acylcarnitine Metabolism in cardiac diseases: From molecular mechanisms to translational potential.
Wu J, Zhang Y, Liu J, Zhao W, Liu X, Dan J. · 2026-09-25
open access unreviewed -
2
Distinct functional roles of <i>Lactobacillus</i> strains in modulating lipid metabolism, adipose accumulation, inflammatory responses, and carcass characteristics in heavy finishing pigs.
Wan B, Zeng Q, He L, Qin X, Tan M, Yan E, Liao J, Li Z, Zhang X, Yin J. · 2026-07-31
open access unreviewed -
3
The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions.
Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Karakuła-Juchnowicz H, Ede G, Grzywacz Ż, Antosik K, Sethi S, Unwin D. · 2026-01-04
cited 10× open access unreviewed -
4
Lipid dysregulation in mouse ovarian antral follicles after oral exposure to a human relevant mixture of three phthalates.
Miller KL, Massey T, Metzler V, Adams A, Liu X, Burns K, Porter LR, Snider J, Craig ZR. · 2026-06-06
cited 3× unreviewed -
5
Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer.
Han Y, Tan TY, Zhang B, Fu YB, Chen W, Yang MH, Wang YQ, Ding YQ, Wang S. · 2026-10-04
open access unreviewed -
6
Important bioactives carnitine and betaine in milk and dairy products: a systematic review based on text mining and topic analysis.
Trapanese L, Salzano A, Cacciola NA, Neglia G, Bifulco G, Balestrieri M, D Occhio MJ, Campanile G. · 2026-10-01
open access unreviewed -
7
Targeting lipid metabolic vulnerabilities with small-molecule inhibitors in acute myeloid leukemia: Emerging insights and therapeutic opportunities.
Yen JH, Phan TQ, Liou JW, Chen PY. · 2026-07-25
open access unreviewed -
8
Relationship Between Hypovitaminosis C, Obesity, and Features of Metabolic Syndrome-A Narrative Review.
Wilson RB, Liang Y, Kaushal D, Carr A. · 2026-10-01
open access unreviewed -
9
Antioxidant Interventions on Muscle Function and Mass in Aging-Related Muscle Decline: A Systematic Review of Preclinical and Clinical Evidence.
Li X, Zhou K, Wong RMY, Cheung WH, Cui C. · 2026-09-15
open access unreviewed -
10
Integrated Metabolomic and Proteomic Analyses Reveal Differential Regulation of the Citrate Cycle and Pentose Phosphate Pathway by <i>Cannabis sativa</i> Extract and the Synthetic Cannabinoid HU210 in GT1-7 Neuronal Cells: Sequential Extraction of Metabolites and Proteins from a Single Cell Pellet.
Natori Y, Mizuno D, Doshi M, Kawahara M, Ishii A. · 2026-09-03
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.