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MS
unreviewed

CDP-choline:DAG cholinephosphotransferase

1 reactions · 1 pathways

What it does, reaction by reaction

1 reactions

Phospholipid Synthesis (Kennedy / CDP pathways) Lipid Metabolism · ER / Golgi

step 3 Irreversible/directional

CDP-choline + 1,2-diacylglycerol -> phosphatidylcholine + CMP

Converts CDP-choline Diacylglycerol into Phosphatidylcholine CMP

› Notes

Principal route to phosphatidylcholine, the main membrane and surfactant phospholipid (DPPC).

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · fetched just now · sorted by publication date

  1. 1
  2. 2
    Lipophagy and lipid droplets in neurodegeneration.

    McKee NW, Jing Y, Serdah R, Thulasingam S, Lopez XS, Tan EP. · 2026-09-22

    unreviewed
  3. 3
    Triphenyl phosphate promotes lipid accumulation in human mesenchymal stem cells through metabolic stress pathways.

    Gronske MC, Stutts W, Jima D, Palumbo J, Stapleton HM, Kullman SW. · 2026-06-02

    open access unreviewed
  4. 4
    Time-Dependent Phospholipid Remodeling in Cultured Primary Mouse Hepatocytes: Associations with PEMT Status and Methionine Availability.

    Ma T, Zhou K, Zhu Y, Zhang J, Xie X, Zhang L, Ye C, Tu ZC. · 2026-09-03

    open access unreviewed
  5. 5
    CaMKIIβ Signaling drives expression of metabolic and stress response genes in skeletal muscle, and its loss contributes to the LGMDR1 phenotype.

    Kramerova I, Anastopulos F, Becerra D, Goldstein de Salazar R, Keeble AR, Chamberlain JS, Moore SA, McNally E… · 2026-09-01

    open access unreviewed
  6. 6
    Subcellular regulation of ferroptosis: roles of individual intracellular organelles and cross talk.

    Piamsiri C, Gwathmey JK, Xie LH. · 2026-07-29

    cited 1× unreviewed
  7. 7
    Chromatin accessibility of the jejunum in two high-yielding laying hen strains under divergent mineral phosphorus supply during the transition to egg laying.

    Abitew YA, Reyer H, Hadlich F, Oster M, Trakooljul N, Sommerfeld V, Rodehutscord M, Wimmers K, Ponsuksili S. · 2026-06-08

    open access unreviewed
  8. 8
  9. 9
    Lipid‑disrupting effects of an organochlorine mixture in Sertoli TM4 cells reveal testicular obesogen mechanisms.

    Virmani I, Sychrová E, Řehůřková E, Gadara D, Spáčil Z, Sovadinová I. · 2026-05-20

    open access unreviewed
  10. 10
    Biosynthesis of Phosphatidylethanolamine and Phosphatidylcholine via the Kennedy Pathway in Cancer and Other Pathological Conditions.

    Korbecki J, Bosiacki M, Chlubek M, Dzięciołowska-Baran E, Lubkowski M, Kabacińska K, Barczak K. · 2026-08-22

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.