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MS
unreviewed

CDP-DAG synthase (CDS1/2)

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Phospholipid Synthesis (Kennedy / CDP pathways) Lipid Metabolism · ER / Golgi

step 4 Irreversible/directional

Phosphatidic acid + CTP -> CDP-diacylglycerol + PPi

Converts Phosphatidic acid CTP into CDP-diacylglycerol PPi

Notes

Alternative activated intermediate used for the acidic phospholipids.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · from cache · sorted by publication date

  1. 1
    Phosphorus Acquisition Strategies Among Phytoplankton and Free-Living Bacterial Communities in the Baltic Proper.

    Thomas M, Hanna F, Elin L, Daniel L, Jarone P, Catherine L. · 2026-04-01

    open access unreviewed
  2. 2
    Tuning the size of quantum dots to enhance charge transfer and photocatalytic CO<sub>2</sub> reduction.

    Khalid MA, Mubeen M, Hussain MN, Mukhtar M, Iqbal A, Kovalenko SA, Palato S, Kandola BK, Iqbal A. · 2026-04-13

    open access unreviewed
  3. 3
    Ferroptosis as a therapeutic vulnerability in ARID1A-deficient bladder cancer.

    Zhao M, Wang X, Duan X, Wu C, Guo R, Wen Y, Liang J, Zhou J, Lei X, Fu S, Wang H, Peng C, Guo C. · 2026-04-10

    open access unreviewed
  4. 4
  5. 5
    Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells.

    Matesanz-Sánchez R, Classen S, Siniuk K, Peitzsch M, Alves T, Pospiech H, Borgmann K, Cordes N. · 2026-03-12

    open access unreviewed
  6. 6
    Preferential use of alkyl-acyl phosphatidylinositol for GPI biosynthesis and diagnostic potential of lipidomics for inherited GPI deficiencies.

    Li X, Imanishi K, Umeshita S, Senoo Y, Guerrero PA, Silva DV, Ikeda K, Kinoshita T, Murakami Y. · 2026-02-05

    open access unreviewed
  7. 7
    Functional effects of EpCAM N-glycosylation in MDA-MB-468 breast cancer cells.

    Jenkinson NM, Oza H, Yarema KJ, Glunde K. · 2026-02-20

    open access unreviewed
  8. 8
    Multi-omics comprehensive analysis identified KIF22 and KRAS as highly synthetic lethal pairs for triple-negative breast cancer.

    Miao S, Wang X, Gu Q, Bian C, Fan R, Ni Q, Wang Y, Zhuang Z. · 2026-02-06

    open access unreviewed
  9. 9
    Advances in Cardiolipin Analysis: Applications in Central Nervous System Disorders and Nutrition Interventions.

    Dong C, Lv D, Dong Y, Zhang Z, Li Q, Chen Z. · 2026-01-01

    cited 1× open access unreviewed
  10. 10
    Synthetic lethality in cancer therapy: Mechanisms, models and clinical translation for overcoming therapeutic resistance.

    Li J, Zhang L, Shang Y, Liu J, Zhao H. · 2026-01-01

    cited 2× open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.