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unreviewed

Beta-alanine transaminase (AGXT2)

1 reactions · 1 pathways

What it does, reaction by reaction

1 reactions

Pyrimidine Degradation Nucleotide Metabolism · Cytosol

step 12 Irreversible/directional

Beta-alanine → malonate semialdehyde → acetyl-CoA

Converts beta-Alanine into Malonate semialdehyde

› Notes

Beta-alanine transaminase (largely AGXT2-associated activity) transfers the amino group of beta-alanine to an alpha-ketoacid acceptor, producing malonate semialdehyde. Malonate-semialdehyde dehydrogenase (ALDH6A1) then catalyzes oxidative decarboxylation of malonate semialdehyde with CoA and NAD+ to form acetyl-CoA, CO2, and NADH; exact transaminase partners vary by tissue.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Foliar application of gamma aminobutyric acid regulates sulfur metabolism and restores redox balance to improve aluminum tolerance in <i>Camelina sativa</i>.

    Murtaza G, Ahmed Z, Hassan NE, Ullah S, Rebouh NY, Alotaibi MS, Alotaibi SS, Ali S, Jafarzadeh S, Iqbal R. · 2026-07-21

    open access unreviewed
  2. 2
    Proteomic mapping of Rosa damascena nanovesicles reveals plastid mitochondrial metabolic convergence and antimicrobial peptides.

    Brahadeeswaran S, Tamizhselvi R. · 2026-03-09

    cited 1× open access unreviewed
  3. 3
    Explaining the unexplained admixture mapping signals via rare variants: the HCHS/SOL.

    Chen X, Argos M, Yu B, Boerwinkle E, Qi Q, Kaplan R, Franceschini N, Sofer T. · 2026-09-01

    unreviewed
  4. 4
    Conjugated Linoleic Acid Alleviates Hepatic Steatosis and Liver Damage in Estradiol-Induced FLHS Roosters by Reshaping Lipid Metabolism and Inhibiting the MAPK/NF-κB-Mediated Inflammation Cascade.

    Liu X, Zhang H, Gao Q, Shang Y, Shi T, Yan P, Fu C. · 2026-09-03

    open access unreviewed
  5. 5
    Genome-Wide Differentiation, Inbreeding, and Candidate Selection Loci in Local Vietnamese Pig Breeds.

    Nguyen VT, Ba NV, Do DN. · 2026-09-04

    open access unreviewed
  6. 6
    Milestones in the Elucidation of Heme Biosynthesis.

    Dailey HA. · 2026-09-01

    open access unreviewed
  7. 7
    Adaptive variation in butyrylcholinesterase-influenced lipid metabolism during horse domestication.

    Zhang Y, Liu X, Wang X, Yu Y, Jia Y, Pu Y, Ma Y, Orlando L, Jiang L. · 2026-08-20

    open access unreviewed
  8. 8
    Asymmetric dimethylarginine (ADMA) modulates frequency-dependent muscarinic antagonism of β-adrenergic regulation of rat papillary muscle contractility

    · 2026-08-13

    open access unreviewed
  9. 9
    Exerkines in precision management of metabolic diseases.

    Jin L, Lin Y, Zheng Y, Wang A, Liao P, Luo Y, Sui Z, Ni X, Zhang J, Shen Q, Xu A. · 2026-08-19

    open access unreviewed
  10. 10
    Integrated Multi-Omics Analysis Reveals Molecular Features Associated with Energy Metabolism Adaptations in Brooding Taihe Black-Bone Silky Fowls.

    Haji RA, Hu J, Ruan J, Liang H, Wan Z, Omar SM, Wei Q, Xie X, Huang Y, Cao J, Huang J. · 2026-08-05

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.