Beta-alanine transaminase (AGXT2)
What it does, reaction by reaction
Pyrimidine Degradation Nucleotide Metabolism · Cytosol
Beta-alanine → malonate semialdehyde → acetyl-CoA
Converts beta-Alanine into Malonate semialdehyde
› Notes
Beta-alanine transaminase (largely AGXT2-associated activity) transfers the amino group of beta-alanine to an alpha-ketoacid acceptor, producing malonate semialdehyde. Malonate-semialdehyde dehydrogenase (ALDH6A1) then catalyzes oxidative decarboxylation of malonate semialdehyde with CoA and NAD+ to form acetyl-CoA, CO2, and NADH; exact transaminase partners vary by tissue.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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