unreviewed
Bacterial 7-alpha-dehydroxylase (colonic microbiota)
1 reactions · 1 pathways
What it does, reaction by reaction
1 reactions
Bile Acid Synthesis Lipid Metabolism · ER + mitochondrion + peroxisome
step 4
Irreversible/directional
Primary bile salts -> deoxycholate and lithocholate (gut bacteria) -> enterohepatic recycling
into Deoxycholate
› Notes
About 95% of bile salts are reabsorbed in the terminal ileum by ASBT and returned to liver; loss of ileum or resin binding forces cholesterol into new bile acid synthesis.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
No articles returned.