Aminotransferase (transaminase), PLP half-reaction 1
Cofactors used
What it does, reaction by reaction
Transamination Amino Acid & Nitrogen Metabolism · Cytosol + mitochondrion
Amino acid + enzyme-bound pyridoxal phosphate (E-PLP) → corresponding α-keto acid + enzyme-bound pyridoxamine phosphate (E-PMP)
Converts Enzyme-bound pyridoxal phosphate into Enzyme-bound pyridoxamine phosphate
› Notes
An aminotransferase (transaminase) forms an external aldimine with the amino acid and transfers its amino group to PLP. PLP (pyridoxal 5′-phosphate; vitamin B6) is essential; this reversible first half-reaction uses no ATP and no free ammonia is produced.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
No articles returned.