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unreviewed

Cytochrome c oxidase (Complex IV)

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Electron Transport Chain (Complexes I–IV)

Accelerated by

ADP, Pi, reduced cytochrome c, O2 availability; low ATP/ADP ratio

Inhibited by

Cyanide, carbon monoxide, azide, hydrogen sulfide; severe hypoxia

Hormonal control

Thyroid hormone and exercise training increase mitochondrial content; acute flux follows ADP availability (respiratory acceptor control)

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Host metabolism shapes the intestinal microbiota: a top-down paradigm of environmental selection pressure.

    Ma Z, Shi H, Bai X, Wang Z, Cao J, Dong Y, Chen Y. · 2026-05-07

    open access unreviewed
  2. 2
    Cuproptosis in spinal cord injury: emerging mechanisms and immunological relevance.

    Li LH, Zhang JQ, Ying XH, Huang Y, Xu CC, Wang XX, He KL, Ma RJ. · 2026-03-25

    open access unreviewed
  3. 3
    The mouse gastric surface epithelial cell and its response to early <i>Helicobacter pylori</i> infection.

    Erhardsson M, Santos L, Benktander J, Sharba S, Thorell K, Lindén S. · 2026-03-25

    open access unreviewed
  4. 4
    Pioneering next-generation bioactive materials for endodontics: Insights of mitochondrial biology.

    Cheng S, Liu XY, Zhou L, Mao HQ, Wen YH, Meng X, Zhang L, Chen Z. · 2026-06-04

    open access unreviewed
  5. 5
    New insights into polycyclic aromatic hydrocarbons: Phenanthrene targets ribosomes to induce neuronal apoptosis.

    Dong Y, Lu H, Wang R, Zhang X, Guo T, Liu H, Dong H, Xing M. · 2026-06-04

    unreviewed
  6. 6
    Multi-omics analyses of evolved <i>Corynebacterium glutamicum</i> mutants reveal the molecular responses to formaldehyde stress.

    Fan L, Cao Q, Zhang Z, Ni X, Lei Y, Shi T, Chen J, Zhang S, Zhou W, Wang Y, Zheng P, Sun J. · 2026-02-10

    open access unreviewed
  7. 7
    Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review).

    Zhu B, Wang C, Liu P, Qu Z, Qi R, Chen S, Niu H. · 2026-06-11

    open access unreviewed
  8. 8
    Selective regulation of partial nitrification/denitrification via light irradiation: Microbial niche differentiation and metabolic adaptation mechanisms.

    Zhuo Y, Shi W, Tang K, Yu Y, Ge S, Qiu S. · 2026-04-14

    unreviewed
  9. 9
    Enzymatic oxygen reduction dominates overpotential-driven thermogenesis in mitochondria.

    Namari NAP, Yan M, Nakamura J, Takeyasu K. · 2026-03-30

    open access unreviewed
  10. 10
    Harnessing Cuproptosis for Antitumor Immunity: A Review of Current Evidence and Therapeutic Strategies.

    Lu I, Zhang J, Chen X, Wang XJ. · 2026-05-15

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.