unreviewed
DHODH
0 reactions · 0 pathways
What it does, reaction by reaction
0 reactions
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
1 entries
Pyrimidine De Novo Synthesis (through to UMP, then CTP/dTMP)
Accelerated by
Dihydroorotate availability and an oxidized mitochondrial CoQ pool
Inhibited by
Leflunomide/teriflunomide, brequinar
Hormonal control
No principal direct hormonal control; respiration and proliferative state influence flux.
Recent literature
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