unreviewed
CPS-II (CAD)
0 reactions · 0 pathways
What it does, reaction by reaction
0 reactions
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
1 entries
Pyrimidine De Novo Synthesis (through to UMP, then CTP/dTMP)
Accelerated by
PRPP and ATP; growth-associated phosphorylation can activate CAD
Inhibited by
UTP (feedback inhibition)
Hormonal control
Mitogen/MAPK signaling can activate CAD by phosphorylation; PKA-mediated phosphorylation is inhibitory in many systems.
Recent literature
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