unreviewed

Renal urate transport (URAT1/GLUT9; not an enzyme)

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

Regulation is pathway-specific, so each context is listed separately

1 entries

Accelerated by

Volume depletion and organic anion exchange can favor urate reabsorption

Inhibited by

Uricosuric drugs such as probenecid/lesinurad inhibit relevant transport

Hormonal control

Insulin resistance and hyperinsulinemia are associated with increased renal urate reabsorption.

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