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unreviewed

HGPRT

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Purine Salvage Pathway

Accelerated by

Availability of hypoxanthine/guanine and PRPP

Inhibited by

Product inhibition by IMP/GMP; low PRPP limits flux

Hormonal control

No important acute hormonal regulation; constitutive activity is critical in neural tissue.

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    Periodic limb movements during sleep in Lesch-Nyhan syndrome.

    Saito Y, Sumitomo N, Saito T, Kimura A, Fukumizu M, Asato S, Kodama K, Matsui K. · 2026-06-12

    cited 1× unreviewed
  2. 2
    Wildfire-Sourced PM2.5 and Emergency Department Visits for Migraine and Other Primary Headache.

    Dales R, Paul N, Cleland SE, Lavigne E, Rouleau M, Evans J, Ferro A, Kunarac K, Owen J, Cakmak S. · 2026-07-01

    unreviewed
  3. 3
    Breeding of Highly Efficient Uric Acid-Lowering Lactic Acid Bacteria by ARTP Mutation and its Transcriptomic Analysis.

    Ding G, Guo S, Yu J, Liang Y, Tang Q, Zeng J, Zhang Z. · 2026-07-08

    unreviewed
  4. 4
    Enteropathy in STAT3 GOF syndrome: Insights into the role of the JAK-STAT pathway.

    Caranfil C, Crepaldi M, Marzollo A, Vogel TP, Schumann M, Palo M, Bertin L, Savarino EV, Pizzi M, Dei Tos A, … · 2026-05-19

    unreviewed
  5. 5
    Primary headaches in juvenile-onset systemic lupus erythematosus: A preliminary case control study using ICHD-3 criteria.

    Menentoğlu B, Kavrul Kayaalp G, Duygu Arık S, Dudaklı A, Baykan C, Akgün Ö, Maraş Genç H, Demirkan FG, Çakmak… · 2026-04-20

    open access unreviewed
  6. 6
    Effects of Mesenchymal Stem Cell-Derived Exosomes on Lung Inflammation in a Murine Aspiration Model.

    Nativ-Zeltzer N, Ueha R, Anderson JD, Nachalon Y, Imai DM, Belafsky PC. · 2026-02-16

    open access unreviewed
  7. 7
    Socioeconomic and regional disparities in the diagnosis of primary arrhythmias in a universal healthcare system: A nation-wide danish study

    · 2026-06-01

    open access unreviewed
  8. 8
    Sustainable Xanthine-Grafted Alginate Biosensing Platform for Metabolic Disorder Diagnostics.

    Ferlazzo A, Saccullo E, Sambataro G, Bruno E, Montaño MD, Abbate V, Failla S, Pistarà V, Gulino A, Rescifina … · 2026-06-01

    open access unreviewed
  9. 9
    Iron-sulfur cofactors in nucleic acid metabolism and protein synthesis: Assembly, delivery, and putative roles in cellular and viral systems.

    Maio N, Rouault TA. · 2026-05-08

    open access unreviewed
  10. 10
    U<b>se of benzodiazepines and medications for opioid use disorder for withdrawal management in a hospital-based setting for individuals exposed to benzodiazepine-contaminated fentanyl: A case serie</b>s.

    Wong A, Nolan S, Bach P, Janssen RM, De Wolfe TJ, Dickhout P, Beauchesne R, Yang F, Johnson C, Carter A, Nosy… · 2026-04-17

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.