unreviewed
MRP2 (canalicular export)
0 reactions · 0 pathways
What it does, reaction by reaction
0 reactions
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
1 entries
Heme Degradation (Bilirubin Pathway)
Accelerated by
ATP and normal canalicular transport capacity
Inhibited by
Cholestasis; MRP2 deficiency; ATP depletion
Hormonal control
Bile-acid and nuclear-receptor signaling influence expression indirectly
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis.
de Haan L, van der Lely SJ, Warps AK, Hofsink Q, Olthof PB, de Keijzer MJ, Lionarons DA, Mendes-Dias L, Bruin… · 2018-02-16
cited 25× open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.