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MS
unreviewed

MRP2 (canalicular export)

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Heme Degradation (Bilirubin Pathway)

Accelerated by

ATP and normal canalicular transport capacity

Inhibited by

Cholestasis; MRP2 deficiency; ATP depletion

Hormonal control

Bile-acid and nuclear-receptor signaling influence expression indirectly

Recent literature

Europe PMC · from cache · sorted by publication date

  1. 1
    Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis.

    de Haan L, van der Lely SJ, Warps AK, Hofsink Q, Olthof PB, de Keijzer MJ, Lionarons DA, Mendes-Dias L, Bruin… · 2018-02-16

    cited 25× open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.