unreviewed
MRP2 (canalicular export)
0 reactions · 0 pathways
What it does, reaction by reaction
0 reactions
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
1 entries
Heme Degradation (Bilirubin Pathway)
Accelerated by
ATP and normal canalicular transport capacity
Inhibited by
Cholestasis; MRP2 deficiency; ATP depletion
Hormonal control
Bile-acid and nuclear-receptor signaling influence expression indirectly
Recent literature
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