unreviewed
Heme oxygenase-1 (HO-1)
0 reactions · 0 pathways
What it does, reaction by reaction
0 reactions
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
1 entries
Heme Degradation (Bilirubin Pathway)
Accelerated by
Heme excess, oxidative stress, hypoxia, inflammatory stimuli
Inhibited by
Reduced heme substrate availability; pharmacologic metalloporphyrins can inhibit
Hormonal control
Stress/inflammatory transcriptional regulation predominates; no central acute endocrine switch
Recent literature
Nothing is fetched until you ask, so the page stays fast and the request is yours rather than automatic.
Europe PMC · ten most recent, newest first