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Heme oxygenase-1 (HO-1)

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Heme Degradation (Bilirubin Pathway)

Accelerated by

Heme excess, oxidative stress, hypoxia, inflammatory stimuli

Inhibited by

Reduced heme substrate availability; pharmacologic metalloporphyrins can inhibit

Hormonal control

Stress/inflammatory transcriptional regulation predominates; no central acute endocrine switch

Recent literature

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