Skip to content
MS
Sign in
unreviewed

Cystathionine β-synthase (CBS)

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Methionine Cycle / Transmethylation (SAM Cycle, homocysteine)

Accelerated by

SAM allosterically activates; PLP sufficiency

Inhibited by

PLP deficiency; pathogenic CBS variants; low substrate

Hormonal control

Liver expression responds to dietary methionine/protein and catabolic state; no dominant rapid systemic hormone

Recent literature

Refresh

Europe PMC · fetched just now · sorted by publication date

  1. 1
    Harnessing gasotransmitters for orthopaedic infection therapy: Mechanisms and advanced delivery platforms.

    Zhang JY, Yang YQ, Zhang ZX, Jin JL, Luo ZY, Wang DY, Ruan CX, Dai TZ, Huang YL, Xu J, Shi JW, Li JY, Lei PF. · 2026-09-03

    open access unreviewed
  2. 2
    A universal consuming endogenous H<sub>2</sub>S strategy using bismuth-metal-organic nanocapsule networks for overcoming osteosarcoma cisplatin resistance.

    Lin Y, Yuan K, Liu Y, Du Y, Chang H, Hou L, Liang Y, Huang K, Yang S, Tang T. · 2026-08-18

    open access unreviewed
  3. 3
    Ferroptosis in major depressive disorder: Molecular mechanisms, cellular vulnerability, and therapeutic opportunities.

    Kong D, Duan R, Wang X, Wang X, Zhao J. · 2026-09-18

    open access unreviewed
  4. 4
    What do we know about redox status? A review in neonates of mothers with preeclampsia.

    Avilés-Garcia JC, Aguilar-Dueñas MF, Ceballos G, Torres-Ramos YD. · 2026-08-26

    open access unreviewed
  5. 5
    Intestinal gases as markers to study the diet-gut microbiota-host metabolism axis in humans and their relationship to metabolic health.

    Larik GNF, Canfora EE, van Schothorst EM, Blaak EE. · 2026-07-14

    open access unreviewed
  6. 6
    Significance of GSH and H<sub>2</sub>S regulation for cancer: an intricate interplay between diet, microbiota, metabolic reprogramming, and immune health.

    Majumder A, Majumder S, Bano S, Sen K, Nayak KB. · 2026-06-11

    open access unreviewed
  7. 7
    Albumin as a dynamic extracellular redox regulator: from Cys34 oxidation biomarkers to polysulfide-mediated homeostatic mechanisms and clinical applications.

    Ishima Y, Watanabe H, Ikeda-Imafuku M, Maeda H, Maruyama T, Otagiri M, Chuang VTG. · 2026-06-02

    open access unreviewed
  8. 8
    A review of the sirtuins family: pivotal regulators and emerging therapeutic targets in renal fibrosis.

    Deng Q, Li C, Luo J, Yin M, Qian S, Li L. · 2026-05-14

    cited 1× open access unreviewed
  9. 9
    <i>Porphyromonas gingivalis</i> secreted factors drive epithelial-mesenchymal transition (EMT) through gingipains and an H<sub><b>2</b></sub>S-mediated bacterial defense system.

    Kazelnik M, Masri R, Caspi M, Wittenstein A, Tsarfaty I, Borenstein E, Caller T, Shatalin K, Nudler E, Rosin-… · 2026-03-24

    open access unreviewed
  10. 10
    Endogenous H₂S promotes HSPA8 sulfhydration to downregulate HIF1α and prevent ferroptosis in septic myocardial injury.

    Jiankui D, Zhang S, Li Z, Li W, Weina L, Miao W, Jian X, Changnan W. · 2026-02-09

    cited 1× open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.