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unreviewed

SHMT

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

One-Carbon Metabolism (Folate Cycle)

Accelerated by

Serine and THF availability; PLP sufficiency

Inhibited by

PLP deficiency; product accumulation

Hormonal control

Growth and nutritional state alter expression and mitochondrial one-carbon flux indirectly

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Isotopic tracing in <i>Mycobacterium tuberculosis</i>-infected alveolar epithelial cells indicates metabolic specificity to their virulence and drug-resistance status.

    Akram S, Masakapalli SK, Nanda RK. · 2026-09-04

    cited 1× open access unreviewed
  2. 2
    Comparative transcriptomic analysis of the gills and hepatopancreas of freshwater-cultured Litopenaeus vannamei under chronic nitrite stress.

    Li X, Li X, Dai X. · 2026-06-22

    unreviewed
  3. 3
    Interactions between nutrition and the epigenome: how can it be harnessed for public health?

    Anastasopoulou M, Dereki I, Sgourou A, Lagoumintzis G. · 2026-03-12

    cited 2× open access unreviewed
  4. 4
    SYVN1-mediated degradation of SHMT2 drives tubular injury progression via metabolic reprogramming.

    Li SS, Chen X, Zhang Q, Tang J, Yu LX, Liu QF. · 2026-08-06

    unreviewed
  5. 5
    Mutations in <i>dfrA</i> and its upstream region are associated with <i>para</i>-aminosalicylic acid resistance in <i>Mycobacterium tuberculosis</i>.

    Zeng R, Ullah N, Gu J, Deng JY. · 2026-09-30

    open access unreviewed
  6. 6
    Endothelial SLC38A2 controls brain D-serine homeostasis and synapse development.

    Tiwari AK, Lahkar A, Sajrawi C, Hussein Y, Majcher A, Bonelli S, Agranovich B, Abramovich I, Stern S, Chaudhr… · 2026-09-09

    open access unreviewed
  7. 7
    Metabolic engineering of <i>Lacticaseibacillus paracasei</i> alleviates post-acidification and reshapes metabolite profiles in probiotic yogurt.

    Li B, Ye L, Dai R, Wang X, Chen Y. · 2026-09-03

    open access unreviewed
  8. 8
    Epitranscriptomic Regulation of ALDOA by SHMT2-Mediated m6A Modification Drives Gastric Cancer Malignancy.

    Li P, Niu C, Zhao D, Wang C. · 2026-08-01

    unreviewed
  9. 9
    Nutrigenomic regulation of one-carbon metabolism and the circadian clock in health and disease.

    Fustin JM. · 2026-10-01

    open access unreviewed
  10. 10
    Oligomeric defects in soybean serine hydroxymethyltransferase 8: tetramer destabilization by A149T and other variants associated with soybean cyst nematode resistance.

    Samarakoon V, Buckley DP, Owuocha LF, Durie CL, Mitchum MG, Beamer LJ. · 2026-03-31

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.