unreviewed
DHFR
0 reactions · 0 pathways
What it does, reaction by reaction
0 reactions
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
1 entries
One-Carbon Metabolism (Folate Cycle)
Accelerated by
DHF accumulation and THF demand
Inhibited by
Methotrexate; trimethoprim; pyrimethamine
Hormonal control
No major acute hormonal regulation; expression rises with proliferative demand
Recent literature
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