unreviewed
MTHFR
0 reactions · 0 pathways
What it does, reaction by reaction
0 reactions
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
1 entries
One-Carbon Metabolism (Folate Cycle)
Accelerated by
S-adenosylmethionine deficiency/low methyl-group availability favors activity; FAD sufficiency
Inhibited by
S-adenosylmethionine allosterically inhibits; folate/riboflavin deficiency reduces activity
Hormonal control
Predominantly nutrient and allosteric regulation; insulin/growth signals influence one-carbon demand indirectly
Recent literature
Nothing is fetched until you ask, so the page stays fast and the request is yours rather than automatic.
Europe PMC · ten most recent, newest first