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unreviewed

Renal glutaminase

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Oxidative Deamination

Accelerated by

Acidosis, glutamine availability

Inhibited by

Alkalosis reduces net ammoniagenic drive

Hormonal control

Cortisol supports renal ammoniagenesis; acid–base status is the dominant physiological regulator

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Hyperammonemia associated with low doses and concentrations of valproic acid in older adults with neurocognitive disorder.

    Coyne S, Das A. · 2026-06-02

    open access unreviewed
  2. 2
    Succinylation - encoded metabolic codes: cracking the molecular logic of cellular adaptation.

    Cong Y, Zhang X, Wang Z, Cui Z, Li C, Han Y, Deng W, Zhou X, Wu H, Sun J, Fan H, Wu G. · 2025-08-26

    cited 2× open access unreviewed
  3. 3
    Valproate-induced hyperammonemic encephalopathy: the role of clinical pharmacists in medication safety-a case report.

    Chen W, Wang D, Fu W, Wang J, Chen M, Li J, Li F. · 2025-07-01

    cited 1× open access unreviewed
  4. 4
    The impact of metabolic reprogramming on tertiary lymphoid structure formation: enhancing cancer immunotherapy.

    Zhang MJ, Wen Y, Sun ZJ. · 2025-04-14

    cited 9× open access unreviewed
  5. 5
    Identification of glutamine as a potential therapeutic target in dry eye disease.

    Chen X, Zhang C, Peng F, Wu L, Zhuo D, Wang L, Zhang M, Li Z, Tian L, Jie Y, Huang Y, Yang X, Li X, Lei F, Ch… · 2025-01-22

    cited 14× open access unreviewed
  6. 6
    Aberrant Energy Metabolism in Tumors and Potential Therapeutic Targets.

    Fan S, Guo J, Nie H, Xiong H, Xia Y. · 2024-11-01

    cited 9× open access unreviewed
  7. 7
    Glutamine metabolism modulates microglial NLRP3 inflammasome activity through mitophagy in Alzheimer's disease.

    Zhang Z, Li M, Li X, Feng Z, Luo G, Wang Y, Gao X. · 2024-10-15

    cited 19× open access unreviewed
  8. 8
    Glutamine and leukemia research: progress and clinical prospects.

    Wang Z, Liu M, Yang Q. · 2024-08-31

    cited 7× open access unreviewed
  9. 9
    Exploiting the Achilles' heel of cancer: disrupting glutamine metabolism for effective cancer treatment.

    Fan Y, Xue H, Li Z, Huo M, Gao H, Guan X. · 2024-03-06

    cited 24× open access unreviewed
  10. 10
    Integrating artificial intelligence into the modernization of traditional Chinese medicine industry: a review.

    Zhou E, Shen Q, Hou Y. · 2024-02-23

    cited 28× open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.