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unreviewed

CETP

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Lipoprotein Metabolism (Exogenous and Endogenous Pathways: chylomicrons, VLDL, LDL, HDL)

Accelerated by

HDL and apoB-particle substrate availability

Inhibited by

CETP inhibitors

Hormonal control

Not primarily under acute hormonal control; activity relates to lipoprotein milieu

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    Structural optimization of cholesteryl ester transfer protein inhibitors: From early scaffolds to advanced clinical candidates.

    Abdollahzadeh M, Ramezani M, Hatamipour M. · 2026-05-08

    unreviewed
  2. 2
    HDL-associated proteins affecting CVD and systemic inflammation.

    Delk SC, Reddy ST. · 2026-08-13

    unreviewed
  3. 3
    In silico discovery of CETP inhibitors from ZINC15 compounds using docking, ADMET filtering, and molecular dynamics simulations.

    Mohammadi K, Nejabat M, Mirabi F, Sahebkar A, Hadizadeh F. · 2026-07-27

    unreviewed
  4. 4
    Reducing CETP activity prevents memory decline in an Alzheimer's disease mouse model.

    Phénix J, Sarty I, Katz MS, Vázquez Cobá A, Marure Rojano AE, Nie H, Kerksiek A, Jerry I, Berger CS, Kiss RS,… · 2026-08-03

    unreviewed
  5. 5
    Targeting the CTBP1-CETP axis overcomes ferroptosis resistance in non-small cell lung cancer by altering lipid accumulation.

    Chen Y, Wang H, Tan X, Yan C, Liu F, Deng S, Wang C, Xia Y, Xu Z, Wu K, Huang S, Chu Q. · 2026-08-01

    unreviewed
  6. 6
    Obicetrapib safety analysis: Pooled phase 3 clinical trial experience.

    Nelson AJ, Kastelein JJ, Ditmarsch M, Hall C, Kling D, Ortiz N, Wicks DL, Hsieh A, Szarek M, Ray KK, Davidson… · 2026-03-24

    unreviewed
  7. 7
    Lipopolysaccharide-binding protein as a biomarker in the diagnosis of necrotizing enterocolitis.

    Zou P, Hou L, Wei P, Song K, Lu J, Zeng J, Liu Y, Zhong X, Chen L, Huang Y, Ouyang Y, Nong T, Tian Y, Li W, L… · 2026-05-26

    unreviewed
  8. 8
    Single-cell transcriptomic insights into lipoprotein transport in yolk sac membrane endodermal epithelial cells of chicken embryos.

    Wu JC, Hu ZQ, Lin YY, Mersmann HJ, Ding ST. · 2026-04-17

    open access unreviewed
  9. 9
    Association of genetically proxied cholesteryl ester transfer protein inhibition with risk of intracranial aneurysms: a Mendelian randomization study.

    Gu X, Wen X, Ma L, Wang D, Li Z, Chen M, Ye G. · 2026-07-28

    unreviewed
  10. 10
    Novel biomarkers for the differential diagnosis of paediatric MYH9-related diseases and immune thrombocytopenia revealed by plasma proteomics.

    Luo X, Cao K, Wang R, Wu W, Huang T, Zhang Y, Fu X, Li D, He M. · 2026-07-27

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.