ATGL
What it does, reaction by reaction
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Triacylglycerol Synthesis and Lipolysis
CGI-58/ABHD5; phosphorylation-dependent perilipin remodeling
G0S2; insulin-mediated suppression
Catecholamines activate cAMP/PKA and mobilize ATGL coactivation; insulin suppresses lipolysis
Recent literature
Europe PMC · from cache · sorted by publication date
-
1
Enhanced lactose utilization from milk enriched in Uridine-5'-monophosphate drives hepatic energy storage in young mammals.
Gao LM, Liu L, Yang XD, Long CM, Wu X. · 2026-06-01
open access unreviewed -
2
The role of protein palmitoylation in disease pathogenesis and therapeutic innovation.
Lin X, Xing J, Jia K, Liu S, Liu Y, Gu Y, Guo K, Yi J. · 2026-05-29
open access unreviewed -
3
A review of the sirtuins family: pivotal regulators and emerging therapeutic targets in renal fibrosis.
Deng Q, Li C, Luo J, Yin M, Qian S, Li L. · 2026-05-14
open access unreviewed -
4
Targeting LRH-1 alleviates diabetes-induced lipotoxicity in podocytes: role of PLIN5-mediated lipid droplet turnover.
Guan Q, Zhu Z, Hu H, Wang J, Fan Y, Ye P, Yang Q, Ding G, Hu J. · 2026-05-14
open access unreviewed -
5
Super-enhancer-associated miR-1260b coordinates adipogenesis and metabolic programming in human adipose stem cells.
Li S, Ji S, Yu Z, Liu H, Wu J. · 2026-03-13
open access unreviewed -
6
Annexin A1 exacerbates islet stellate cell activation by regulating triglyceride catabolism via the PPARα/ACOX1/CYP4a pathway.
Li Q, Zhang Y, Yu T, Shi L, Qiu Q, Wang B, Sang Y, Li R, Lv Q, Wang J, Liu X, Geng H, Jones PM, Liang J, Xu W. · 2026-02-22
open access unreviewed -
7
An acute temperature rise to 40°C inhibits free fatty acid uptake into white adipocytes.
Foti F, Schaepper RS, Konrad D, Wueest S. · 2026-02-11
open access unreviewed -
8
GPR3 in neuro-metabolic-immune-reproductive nexus - a potential therapeutic target for Multi-System diseases.
Feng BD, Qin JY, Qin QQ, Xu ZC, Zhang HQ. · 2026-01-23
cited 1× open access unreviewed -
9
cAMP-PKA/EPAC signaling pathways: crucial regulators of lipid homeostasis.
Chen C, Gao H, Tian Q, Cao J. · 2026-01-07
open access unreviewed -
10
Protective role of alpha-linolenic acid against ATGL inhibition-induced lipid accumulation and developmental defects in porcine oocytes.
Gao LP, Sun JT, Wang YY, Zhang CY, Yin Z, Liu ZH, Dong XF, Song J, Jin JX. · 2026-05-14
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.