unreviewed

DGAT1/DGAT2

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Triacylglycerol Synthesis and Lipolysis

Accelerated by

DAG and acyl-CoA availability

Inhibited by

Limited acyl-CoA; pharmacologic DGAT inhibition

Hormonal control

Insulin and feeding favor TAG assembly; glucagon/epinephrine indirectly reduce it by mobilizing stores

Recent literature

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Europe PMC · fetched just now · sorted by publication date

1
Early postnatal antibiotic-associated gut microbiota alterations might promote long-term lipid metabolism via brown adipose tissue metabolic programming.
Liang H, Jiang F, Ren L, Li X, Wu S, Li J, Li L, Ze X, Shen X, He F. · 2026-05-04

open access unreviewed
2
Annexin A1 exacerbates islet stellate cell activation by regulating triglyceride catabolism via the PPARα/ACOX1/CYP4a pathway.
Li Q, Zhang Y, Yu T, Shi L, Qiu Q, Wang B, Sang Y, Li R, Lv Q, Wang J, Liu X, Geng H, Jones PM, Liang J, Xu W. · 2026-02-22

open access unreviewed
3
Diacylglycerol enantiomer selectivity of diacylglycerol acyltransferases highlights metabolic specialization in triacylglycerol synthesis across the tree of life.
Parchuri P, Shockey J, Durrett TP, Bates PD. · 2026-07-01

open access unreviewed
4
Micro- and Nanoplastics as Emerging Drivers of Liver Injury: Exposure, Evidence, and Mechanisms
Badach M, Banaszek J, Barańska K, Kleinrok J, Flieger M, Flieger J, Teresiński G, Forma A, Sitarz R, Baj J. · 2026-06-01

open access unreviewed
5
Fatty acid esters of hydroxy fatty acids and alkyl-diacylglycerols: minor but bioactive components in human milk.
Lee MLX, Elejalde U, Cazenave-Gassiot A. · 2026-06-01

open access unreviewed
6
Hepatic Lipoprotein Production, Cardiometabolic Phenotypes, and Subtypes of Steatotic Liver Disease.
Davidson NO. · 2026-06-04

cited 1× unreviewed
7
The mTOR-Dop1a-Agpat2 axis regulates nuclear phospholipid homeostasis.
Ariyama H, Tsukamura A, Miyatake S, Okado S, Itabashi I, Ogura A, Suzuki A, Kurakawa H, Sakaguchi Y, Nakatake… · 2026-04-22

open access unreviewed
8
ACSS2 governs milk fat synthesis in buffalo via a reciprocal positive feedback loop with SREBP1 and PPARG.
Huang L, Wang R, Zhou F, Gao R, Fan X, Miao Y. · 2026-03-11

open access unreviewed
9
Fatty acid in the intramuscular and abdominal fat of chickens: their composition, deposition, regulation and impact on flavor.
Zou J, Li H, Zhang X. · 2026-05-25

open access unreviewed
10
Opposite diacylglycerol enantiomeric specificities of Arabidopsis DGAT1 and DGAT2 reveal distinct roles in TAG synthesis.
Jaison CA, Björklund J, Stymne S, Demski K, Hofvander P, Lager I. · 2026-05-01

open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.