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unreviewed

Squalene synthase

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Cholesterol Biosynthesis (Mevalonate Pathway)

Accelerated by

FPP availability

Inhibited by

Sterol feedback and pathway-specific inhibitors

Hormonal control

Fed-state/insulin signaling tends to favor expression; fasting suppresses lipogenic/sterol programs

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Yeast species resource exploration and application in cell factories.

    Zhang M, Xiang L, Qin L, Yue H, Li C. · 2026-03-11

    cited 1× open access unreviewed
  2. 2
    Utilization, metabolic regulation and applications of hydrophobic substrates in <i>Yarrowia lipolytica</i>.

    Zhu F, Zhang L, Wen J. · 2026-02-18

    open access unreviewed
  3. 3
    Metabolic and transport engineering enable efficient de novo biosynthesis of patchoulol in <i>Saccharomyces cerevisiae</i>.

    Fu D, Zhou Y, Wu Z, Wang S, Lao Y, Wang HB, Jin HL. · 2026-02-09

    cited 1× open access unreviewed
  4. 4
    Construction of a globally modular recombinant <i>Saccharomyces cerevisiae</i> chassis for ginkgolide precursor levopimaradiene production.

    Liu, Chen Z, Guo Z, Xue Q, He Q, Yu R, Zhu J. · 2026-02-05

    open access unreviewed
  5. 5
    Metabolic engineering and adaptive laboratory evolution enhance squalene production in <i>Yarrowia lipolytica</i>.

    Zhao QQ, Hu PC, Zhang CJ, Zhu MY, Tian Y, Yang XN, Ji XJ, Li CZ, Sun XM, Lu XY, Liu HH. · 2026-01-30

    open access unreviewed
  6. 6
    Β-Sitosterol-imidazolium ionic liquid conjugates: synthesis, computational evaluation, and anticancer activity against colorectal cancer cells.

    Seervi S, Vyas S, Rana N, Manhas A, Patel DD, Banerjee J, Mishra R, Banerjee S. · 2026-07-22

    unreviewed
  7. 7
    Low temperature rather than hypoxia drives cholesterol synthesis and oxygen consumption in plateau zokors.

    Hu Q, Wei L, An Z, Wang Y, Zhang T, Wei D. · 2026-06-11

    open access unreviewed
  8. 8
    Total and engineered biosynthesis of cinatrins: inhibitors of phospholipase A<sub>2</sub> and squalene synthase.

    Heinemann H, Gerlach N, Kuhnert E, Gerke J, Verwaaijen B, Kalinowski J, Stadler M, Cox RJ. · 2026-05-08

    open access unreviewed
  9. 9
    Emerging roles of the metabolic regulator 3-hydroxy-3-methylglutaryl coenzyme-CoA reductase in human cancers: From biology to therapeutics.

    Li W, Xu J, Long Y, Zhang H, Rong X, Su Z. · 2025-11-19

    cited 1× open access unreviewed
  10. 10
    Development of a CRISPRi system in <i>Fusarium fujikuroi</i> and its application in gibberellic acid production.

    Cen Y, Xiao H, Jia J, Mou J, Li H, Wang J, Yi Y, Li M, Liu Z, Zheng Y. · 2026-01-21

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.