Squalene synthase
What it does, reaction by reaction
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Cholesterol Biosynthesis (Mevalonate Pathway)
FPP availability
Sterol feedback and pathway-specific inhibitors
Fed-state/insulin signaling tends to favor expression; fasting suppresses lipogenic/sterol programs
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Highly efficient production of <i>β</i>-caryophyllene in <i>Saccharomyces cerevisiae</i> using a novel synthase from <i>Artemisia argyi</i>.
Xiao X, Wan X, Lu H, Cheng W, Liu J, Jiang H, Zhi Y, Chen F, Yang J, Er L, Lu L, Yao G. · 2026-06-25
open access unreviewed -
2
IgA deficiency reveals a microbiota-dependent pathway to gluten sensitivity.
Ball RAW, Mohammed AD, Jolly A, Johnson K, Sklenicka S, Kucherina M, Peacock T, Liu E, Hogan KM, Baird M, Peñ… · 2026-09-18
open access unreviewed -
3
Ferroptosis in liver biology and diseases.
Cao P, He P, Du K, Jaeschke H, Lemasters JJ, Chen Y, Wong CC, Ding WX. · 2026-09-28
open access unreviewed -
4
Targeting lipid metabolic vulnerabilities with small-molecule inhibitors in acute myeloid leukemia: Emerging insights and therapeutic opportunities.
Yen JH, Phan TQ, Liou JW, Chen PY. · 2026-07-25
open access unreviewed -
5
Evolution-Inspired Engineering of Diterpene Biosynthesis via Chloroplast Genome Modification.
Occhialini A, Chen X, Miller SA, Majdi M, Fuentes Quispe IA, King G, Chen F. · 2026-07-19
open access unreviewed -
6
Lipid Metabolic Reprogramming in Lung Cancer: Mechanisms and Therapeutic Targets in the Tumor Microenvironment.
Wang S, Yu J. · 2026-06-02
unreviewed -
7
A RUBY-Based Visual Hairy Root Transformation and CRISPR-<i>PTG</i> Genome-Editing System in <i>Eucommia ulmoides</i>.
Xu L, Zhou Y, Sun Y, Dong Y, Kang R, Yao N, Cai X. · 2026-09-11
open access unreviewed -
8
Functional Characterization and Promoter Analysis of a MeJA-Responsive Squalene Synthase Gene <i>CpSQS</i> from <i>Cyclocarya paliurus</i> (Batal.) Iljinsk.
Chen J, Xia Q, Dong Y, Pan Y, Lv Q, Huang J, Zhang S, Dong X, Chen X. · 2026-09-21
open access unreviewed -
9
Comparative Genomics Reveals Extensive Biosynthetic Diversity and Lineage-Specific Metabolic Potential Across <i>Talaromyces</i> Species.
Chellappan BV, Al-Sheikh H. · 2026-09-14
open access unreviewed -
10
Insights into Enzymes Involved in the Biosynthesis of Protopanaxadiol-Type Ginsenosides in <i>Panax</i> Species.
Li N, Jiang X, Gao S, Chen Q, Ge F, Cui X. · 2026-09-02
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.