unreviewed

CPT-1

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

Regulation is pathway-specific, so each context is listed separately

2 entries

Accelerated by

Low malonyl-CoA; increased fatty-acyl-CoA supply

Inhibited by

Malonyl-CoA (potent allosteric inhibitor)

Hormonal control

Glucagon/epinephrine favor oxidation indirectly by lowering ACC activity and malonyl-CoA; insulin raises malonyl-CoA and restrains CPT-1

Accelerated by

Low malonyl-CoA, fatty-acyl-CoA availability

Inhibited by

Malonyl-CoA

Hormonal control

Glucagon/epinephrine lower malonyl-CoA and increase fatty-acid entry; insulin opposes this

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