Fatty acid synthase
What it does, reaction by reaction
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Fatty Acid Synthesis (De Novo Lipogenesis)
Carbohydrate abundance; SREBP-1c and ChREBP transcriptional activation
Product long-chain acyl-CoA feedback at the pathway level
Insulin induces FAS; glucagon and fasting reduce expression
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Strategy for enhanced production of A40926B0 in <i>Nonomuraea gerenzanensis</i> using an efficient CRISPR/AsCas12f1 system.
Wang X, Zhai H, Gu D, Wang Y, Gao J, Du L, Zhuo L, Li X, Wang Y. · 2026-08-24
open access unreviewed -
2
System reconstruction of <i>Bacillus licheniformis</i> for efficient expression of alkaline protease.
Zhang Q, Zhang M, Zhu Z, Ma H, Mo F, Lei J, He S, Liao Y, Yan S, Cai D, Chen S. · 2026-08-01
open access unreviewed -
3
3D-printed niche-matched GelMA-dECM bioinks rewire lipid metabolic reprogramming and chemosensitization in pancreatic ductal adenocarcinoma.
Zhu B, Yang T, Chang M, Li Y, Wu D, Yan J, Guo Q, Wan J, Guo Y, Lu Y. · 2026-08-20
unreviewed -
4
Tailored biosynthesis of medium chain oleochemicals by engineering fatty acid synthase and β-oxidation.
Cui S, Gao J, Yang X. · 2026-07-29
open access unreviewed -
5
Engineering nonconventional yeasts to produce carboxylic acids: Advances and Prospects.
Zhang L, Fan Y, Shi W, Zhou X. · 2026-07-16
open access unreviewed -
6
VCP at the crossroads of UPS and autophagy in cancer.
Hitchman CJ, Phillips JI, Park HW, Lu H. · 2026-05-28
open access unreviewed -
7
Metabolic reprogramming in colorectal cancer: Mechanisms and therapeutic insights.
Xiao W, Tan D, Zeng W, Nie X, Wang M. · 2026-01-28
open access unreviewed -
8
Pharmacological inhibition of CLPP stabilizes LETMD1 to boost thermogenesis and alleviate obesity.
Yuan H, Deng Y, Wang J, Luan B, Zhang ZN. · 2026-09-30
open access unreviewed -
9
Low-dose l-carnitine supplementation attenuates hepatic lipid accumulation in chow-fed mice: Insights from integrated multi-omics analysis.
Zhang Z, Ding B, Zhang L, Zhang L, Huang Y. · 2026-09-10
open access unreviewed -
10
From candidate genes to whole-genome approaches: current insights into the genetic architecture of ovine milk production and quality traits.
Mastrangelo S, Benanti A, Tumino S, Criscione A, Cesarani A. · 2026-09-15
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.