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unreviewed

Fatty acid synthase

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Fatty Acid Synthesis (De Novo Lipogenesis)

Accelerated by

Carbohydrate abundance; SREBP-1c and ChREBP transcriptional activation

Inhibited by

Product long-chain acyl-CoA feedback at the pathway level

Hormonal control

Insulin induces FAS; glucagon and fasting reduce expression

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    Tailored biosynthesis of medium chain oleochemicals by engineering fatty acid synthase and β-oxidation.

    Cui S, Gao J, Yang X. · 2026-07-29

    unreviewed
  2. 2
    Mitochondria-related pathogenic genes in acute and chronic kidney disease: a Mendelian randomization study.

    Wang J, Yuan T, Wei Q, Xie K, Zhang J. · 2026-07-08

    unreviewed
  3. 3
    Thraustochytrid PUFA synthase ER domains form a stable heterodimer.

    Lofeudo N, Moncalian G. · 2026-06-10

    unreviewed
  4. 4
    Multi-omics characterization of glucose-lipid metabolic remodeling associated with Gymnema sylvestre (Retz.) R.Br. ex Sm. treatment in a type 2 diabetic mouse model.

    Zeng Z, Liu Y, Xiao G, Jia C, Wu M, Li Y, Jiang J, Zhang J, Xu A, Bi X. · 2026-06-20

    unreviewed
  5. 5
    Enhanced lactose utilization from milk enriched in Uridine-5'-monophosphate drives hepatic energy storage in young mammals.

    Gao LM, Liu L, Yang XD, Long CM, Wu X. · 2026-06-01

    open access unreviewed
  6. 6
    STARD10 promotes progression of HER2+ breast cancer and intracellular lipid metabolism via the cAMP/PKA/CREB1 signaling axis.

    Liu S, Gao J, Niu Y, Dong X, Zhang Z, Teng X, Li Z, Zhang S, Meng Y, Gao MQ. · 2026-06-15

    open access unreviewed
  7. 7
    MITF-Driven melanoma plasticity as a core mechanism of therapy resistance: integrating microenvironmental signaling, mechanotransduction, and metabolic reprogramming.

    Kisielewska M, Suwała S, Drąg-Zalesińska M, Rembiałkowska N. · 2026-06-15

    open access unreviewed
  8. 8
    Integrated transcriptome and metabolome reveal <i>Mycoplasma hyopneumoniae</i> -induced lipid accumulation, inflammation, oxidative stress, and energy imbalance in the liver of pigs.

    Xue X, Bu Y, Yu C, Li J, Yang J, Gao M, Wang P, Gan Y, Zhang W, Fan S, Zhou R, Yin Z, Zheng X. · 2026-06-03

    open access unreviewed
  9. 9
    Multi-omics integration reveals convergent extracellular matrix remodelling and lipid metabolic reprogramming as central axes of adipocyte differentiation from mouse embryonic stem cells.

    Al-Sayegh M, Khalili M, Alzaabi M, Sultana M, Ali L, Ali M, El-Hadidi M. · 2026-06-02

    open access unreviewed
  10. 10
    The role of protein palmitoylation in disease pathogenesis and therapeutic innovation.

    Lin X, Xing J, Jia K, Liu S, Liu Y, Gu Y, Guo K, Yi J. · 2026-05-29

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.