Fructokinase (ketohexokinase)
What it does, reaction by reaction
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Fructose Metabolism (Fructolysis)
Substrate availability
No important physiological allosteric inhibitor
No dominant acute hormonal control; hepatic flux depends largely on fructose delivery
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
The association between high fructose corn syrup and the development of type-2 diabetes.
Almansouri M. · 2026-03-17
open access unreviewed -
2
Fish oil rich in ω-3 fatty acid alleviates long-term high fructose consumption-induced fatty liver and kidney dysfunction in rats.
Liu SH, Hung RW, Chang TY, Chiang MT. · 2025-12-01
open access unreviewed -
3
The interplay between nutrigenomics and low-carbohydrate ketogenic diets in personalized healthcare.
Almoghrabi YM, Eldakhakhny BM, Bima AI, Sakr H, Ajabnoor GMA, Gad HM, Mohammad FAH, Elsamanoudy SA, Awan AZ, … · 2025-06-23
cited 2× open access unreviewed -
4
A high-fat plus high-sucrose diet induces age-related macular degeneration in an experimental rabbit model.
Wang Y, Lv Z, Chen Y, Cen X, Zhang H, Chen D. · 2024-11-27
cited 6× open access unreviewed -
5
Endogenous Fructose Production and Metabolism Drive Metabolic Dysregulation and Liver Disease in Mice with Hereditary Fructose Intolerance.
Andres-Hernando A, Orlicky DJ, Kuwabara M, Cicerchi C, Pedler M, Petrash MJ, Johnson RJ, Tolan DR, Lanaspa MA. · 2023-10-16
cited 9× open access unreviewed -
6
Non-alcoholic fatty liver disease and diabetes mellitus as growing aetiologies of hepatocellular carcinoma.
Talamantes S, Lisjak M, Gilglioni EH, Llamoza-Torres CJ, Ramos-Molina B, Gurzov EN. · 2023-06-09
cited 43× open access unreviewed -
7
THE THERAPEUTIC EFFECT OF ALLOPURINOL IN FATTY LIVER DISEASE IN RATS.
Barişik V, Korkmaz HA, Çekdemir YE, Torlak D, Aktuğ H, Yavaşoğlu A, Erbaş O. · 2023-04-01
cited 2× unreviewed -
8
Fructose might be a clue to the origin of preeclampsia insights from nature and evolution.
Nakagawa T, Ana Andres-Hernando, Kosugi T, Sanchez-Lozada LG, Stenvinkel P, Kublickiene K, Ananth Karumanchi … · 2022-12-20
cited 10× unreviewed -
9
Association between serum ferritin and uric acid levels and nonalcoholic fatty liver disease in the Chinese population.
Zhou F, He X, Liu D, Ye Y, Tian H, Tian L. · 2023-10-26
cited 4× open access unreviewed -
10
Maternal Fructose Intake, Programmed Mitochondrial Function and Predisposition to Adult Disease.
Smith EVL, Dyson RM, Weth FR, Berry MJ, Gray C. · 2022-10-13
cited 10× open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.