Phosphorylase kinase
What it does, reaction by reaction
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Glycogenolysis (Glycogen Breakdown)
Ca2+–calmodulin, phosphorylation by protein kinase A
Dephosphorylation by protein phosphatase 1
Epinephrine and glucagon (liver) promote cAMP/protein kinase A activation; insulin favors inactivation
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Targeting PHKA2 by Thymol alleviates sepsis induced cardiomyocyte pyroptosis via FOXA1/KLF4-mediated macrophage polarization.
Zhu H, Han S, Xue C, Hou Z, Peng X, Sun H, Zhang B, Zhang L, Qiao X, Wang L, Feng G, Zhang Y, Liu J, Liu Z, J… · 2026-06-24
unreviewed -
2
RNA-based therapeutics for Alzheimer's disease and related tauopathies: challenges and opportunities.
Rajbanshi B, Brentari I, Denti MA, Cummings JL, Guruacharya A. · 2026-05-07
cited 1× open access unreviewed -
3
Hepatic Glycogen Storage Disease Type IX: Long-Term Outcomes in the UK From 89 Patients.
Halligan RK, Sanders MT, Selvanathan A, Veeraghavan N, Bernhardt I, Gribben J, Ramachandran R, White FJ, Schw… · 2026-07-01
unreviewed -
4
Cardiomyopathy in glycogen storage diseases: diagnosis, prognosis, and advanced management.
Patel U, Gunes E, Chawla A, Ashman K, Taub A, Arakelyan T, Madani A, Patel K, Bui Q, Adler E. · 2026-07-10
unreviewed -
5
Modulation of the tumor microenvironment by incretins and glucagon: Metabolic and immune mechanisms (Review).
Hu M, Jiang CJ, Yi C. · 2026-05-08
open access unreviewed -
6
Transcriptomic Analysis Reveals Molecular Mechanisms of Fleeing, Adhesion, and Thanatosis Patterns in Sea Cucumber <i>Apostichopus japonicus</i>.
Wu G, Wu H, Wang X, Gao Q, Zhao C. · 2026-06-22
open access unreviewed -
7
Chitosan Oligosaccharides Suppress Adipogenesis and Lipid Accumulation in 3T3-L1 Preadipocytes via Multi-Pathway Transcriptomic Reprogramming.
Songkoomkrong S, Nonkhwao S, Saetan J, Duangprom S, Amonruttanapun P, Janpan P, Sobhon P, Kornthong N. · 2026-05-30
open access unreviewed -
8
Dietary and Therapeutic Management of Glycogen Storage Disease Type IX: Analysis of a Systematic Review.
Montanari G, Zanaroli A, Candela E, Biasucci G, Baronio F, Ortolano R, Lanari M. · 2026-05-05
open access unreviewed -
9
The genomic basis of independent marine transitions in turtles: convergent episodic adaptation and demographic shifts.
Ramos E, Hilgers L, Carrasco-Valenzuela T, De Panis D, Picorelli A, Sullivan J, Uliano-Silva M, Bentley BP, S… · 2026-05-01
open access unreviewed -
10
A <i>Caenorhabditis elegans</i> spatiotemporal proximity atlas reveals the MAPK p38 as a generator of phenotypic plasticity in vivo.
Yuan W, Nunamaker LA, Weaver YM, Weaver BP. · 2026-05-05
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.