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unreviewed

Phosphorylase kinase

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Glycogenolysis (Glycogen Breakdown)

Accelerated by

Ca2+–calmodulin, phosphorylation by protein kinase A

Inhibited by

Dephosphorylation by protein phosphatase 1

Hormonal control

Epinephrine and glucagon (liver) promote cAMP/protein kinase A activation; insulin favors inactivation

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Multimodality Molecular Profiling Nominates Targetable Mechanisms in Progressive RV Dysfunction

    Blake M, Mendelson J, Sternbach J, Kim M, Raveendran R, Moon R, Hartweck L, Tollison W, Carney J, Markowski T… · 2026-10-07

    unreviewed
  2. 2
    Ferroptosis in liver biology and diseases.

    Cao P, He P, Du K, Jaeschke H, Lemasters JJ, Chen Y, Wong CC, Ding WX. · 2026-09-28

    open access unreviewed
  3. 3
    MiR-145-5p modulates collagen production and fibroblast behaviour after cardiac injury partially via COL5A1.

    Wang H, Paavola J, Perttunen S, Immonen K, Hägerström I, Narumanchi S, Kalervo K, Tolva J, Sinisalo J, Mäyrän… · 2026-08-03

    open access unreviewed
  4. 4
    Iron chaperones and RNA-binding proteins, PCBP1 and PCBP2, maintain hepatic iron balance and protect against ferroptosis.

    Protchenko O, Tietgens AJ, Messager E, Jadhav S, Kleiner DE, Grounds S, Shakoury-Elizeh M, Philpott CC. · 2026-06-30

    cited 1× unreviewed
  5. 5
    Dietary halloysite supplementation in Orvia ducks: effects on production performance, meat quality, blood biochemistry, muscle histological and molecular traits.

    Wlaźlak S, Dunisławska A, Pietrzak E, Yatsenko O, Tuśnio A, Barszcz M, Święch E, Gawin K, Konopka A, Adamski … · 2026-09-12

    open access unreviewed
  6. 6
    Assessing the therapeutic potential of PDE-5 inhibitors in adults: Insights from a multi-omics study.

    McGovern KA, Wright TJ, Marchant ED, Kilroe SP, Durham WJ, Dillon EL, Baum MM, Kinsky MP, Russell WK, Fry CS,… · 2026-09-01

    open access unreviewed
  7. 7
    Targeting PHKA2 by Thymol alleviates sepsis induced cardiomyocyte pyroptosis via FOXA1/KLF4-mediated macrophage polarization.

    Zhu H, Han S, Xue C, Hou Z, Peng X, Sun H, Zhang B, Zhang L, Qiao X, Wang L, Feng G, Zhang Y, Liu J, Liu Z, J… · 2026-06-24

    unreviewed
  8. 8
    RNA sequencing resolves a novel noncanonical splice-region variant in <i>PHKA2</i> causing glycogen storage disease type IX α2: a case report.

    Chen F, He J, Cheng H, Shu S. · 2026-07-10

    open access unreviewed
  9. 9
    Hepatic metabolic adaptation to endurance exercise: temporal and sex differences by multiomics integration and validation.

    Gao Y, Tu Z, Zhao Q, Peng J, Shu Y, Ren J, Deng X, Chen Y, Zhou Y, Zeng H, Chen B, Hao L. · 2026-08-25

    open access unreviewed
  10. 10
    Pathological Mechanisms and Therapeutic Potential of Mitochondrial Dysfunction in Heart Failure.

    San S, Yang X, Shen L, Meng K. · 2026-08-21

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.