Pyruvate carboxylase
What it does, reaction by reaction
This enzyme appears only in the regulation table, with no catalysed step recorded.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Gluconeogenesis
Acetyl-CoA
Low acetyl-CoA availability; ADP decreases gluconeogenic flux
Glucagon indirectly favors flux by promoting fatty-acid oxidation and acetyl-CoA production; insulin suppresses gluconeogenic program
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Unlocking raw-corncob consolidated bioprocessing for malic acid production by DyP-enabled lignin deconstruction in <i>Myceliophthora thermophila</i>.
Zhang Y, Zhang Y, Han L, Liu J, Liu D, Sun T, Wang D, Li M, Li J, Tian C. · 2026-08-08
open access unreviewed -
2
Engineering nonconventional yeasts to produce carboxylic acids: Advances and Prospects.
Zhang L, Fan Y, Shi W, Zhou X. · 2026-07-16
open access unreviewed -
3
Effects of dietary supplementation with fat powder with different n-6/n-3 polyunsaturated fatty acid ratios on the reproductive performance of sows and intestinal health of piglets.
Li Y, Zhao S, Wang F, Zeng X, Zhang Y, Cai S. · 2026-08-01
open access unreviewed -
4
Distinct metabolomic signatures of SGLT2 inhibitor vs. sulfonylurea in a paired human liver biopsy study.
Takeshita Y, Oo HK, Nakano Y, Ueno A, Oishi M, Tsujiguchi H, Soga T, Yamashita T, Honda M, Takamura T. · 2026-09-14
open access unreviewed -
5
Lactylation in influenza a virus infection: Current evidence, knowledge gaps, and future perspectives.
Yan YC, Li Z, He H, Wu M, Yang H, Wei F. · 2026-08-02
open access unreviewed -
6
Pathogenicity and virulence of <i>Candida auris</i>.
Phan-Canh T, Seiser S, Chauhan M, Kuchler K, Chauhan N, Elbe-Bürger A. · 2026-07-31
open access unreviewed -
7
Photosynthetic production of glutamine through metabolic analysis-based engineering of <i>Picosynechococcus</i> sp. PCC 7002.
Kato Y, Tsuji A, Haraguchi Y, Shimizu T, Kondo A, Hasunuma T. · 2026-06-17
open access unreviewed -
8
A commensal protozoan exacerbates acetaminophen-induced liver injury by producing free sphingosine.
Yan X, Shen Y, Sun Q, Zhu X, Chen Q, Liao L, Zhou Y, Cheng W, Shi Z, Liu Z, Wei Y, Liu X, Wang Y, Kou Y. · 2026-06-02
open access unreviewed -
9
Salvianolic acid C alleviates acute kidney injury by restoring fructose-1,6-bisphosphatase 1-mediated gluconeogenesis.
Chen J, Li Y, Zhou P, Zou S, Zhao J, Wu M, Wang L. · 2026-03-08
cited 1× open access unreviewed -
10
Advancements in early biomarkers of acute kidney injury: from traditional indicators to a paradigm shift in lactate metabolism.
Wu Q, Qiu X, Chen H. · 2026-01-13
cited 5× open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.