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unreviewed

Pyruvate carboxylase

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Gluconeogenesis

Accelerated by

Acetyl-CoA

Inhibited by

Low acetyl-CoA availability; ADP decreases gluconeogenic flux

Hormonal control

Glucagon indirectly favors flux by promoting fatty-acid oxidation and acetyl-CoA production; insulin suppresses gluconeogenic program

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    Photosynthetic production of glutamine through metabolic analysis-based engineering of <i>Picosynechococcus</i> sp. PCC 7002.

    Kato Y, Tsuji A, Haraguchi Y, Shimizu T, Kondo A, Hasunuma T. · 2026-06-17

    unreviewed
  2. 2
    A commensal protozoan exacerbates acetaminophen-induced liver injury by producing free sphingosine.

    Yan X, Shen Y, Sun Q, Zhu X, Chen Q, Liao L, Zhou Y, Cheng W, Shi Z, Liu Z, Wei Y, Liu X, Wang Y, Kou Y. · 2026-06-02

    open access unreviewed
  3. 3
    Salvianolic acid C alleviates acute kidney injury by restoring fructose-1,6-bisphosphatase 1-mediated gluconeogenesis.

    Chen J, Li Y, Zhou P, Zou S, Zhao J, Wu M, Wang L. · 2026-03-08

    open access unreviewed
  4. 4
    Advancements in early biomarkers of acute kidney injury: from traditional indicators to a paradigm shift in lactate metabolism.

    Wu Q, Qiu X, Chen H. · 2026-01-13

    cited 2× open access unreviewed
  5. 5
    The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions.

    Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Karakuła-Juchnowicz H, Ede G, Grzywacz Ż, Antosik K, Sethi S, Unwin D. · 2026-01-04

    cited 4× open access unreviewed
  6. 6
    Erianin inhibits 3T3-L1 adipocyte differentiation through downregulation of CCAAT-enhancer binding protein-α and peroxisome proliferator-activated receptor-γ, lipogenic genes and impairment of mitochondrial respiration.

    Yimpreeda H, Laowittawat C, Siritutsoontorn S, Rojvirat P, Kumphune S, Jitrapakdee S. · 2025-12-19

    open access unreviewed
  7. 7
    Electroconvulsive Treatment for Depression Alters Mitochondrial Serum Metabolites.

    Pålsson E, Sigström R, Salehi A, Hedenström M, Nordenskjöld A, Landén M. · 2026-05-12

    open access unreviewed
  8. 8
    Enzyme promiscuity-driven co-production of flavonoid 7-<i>O</i>-glycosides in engineered <i>Saccharomyces cerevisiae</i>.

    Tan X, Zuo S, Hu F, Xiao Z, Wang Y, Zhang S, Lu Q, Zhao Y, Chen J, Fan L, Liu J, Shan Y. · 2026-02-12

    cited 1× open access unreviewed
  9. 9
    Sustainable production of glutaric acid in microbial cell factories: Current advances and future prospects.

    Liu J, Mei D, Zhang XJ, Zhang WG, Zhu LB. · 2026-01-23

    open access unreviewed
  10. 10
    Metabolic Programming of β-Cell Fate, State, and Function through Time and Space.

    MacDonald TL, Bonner-Weir S. · 2026-01-16

    cited 1× unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.