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MS
unreviewed

Glucokinase (liver)

0 reactions · 0 pathways

What it does, reaction by reaction

0 reactions

This enzyme appears only in the regulation table, with no catalysed step recorded.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Glycolysis

Accelerated by

High portal glucose; release from glucokinase regulatory protein by fructose-1-phosphate

Inhibited by

Fructose-6-phosphate promotes nuclear sequestration through glucokinase regulatory protein

Hormonal control

Insulin induces expression; glucagon lowers expression during fasting

Recent literature

Europe PMC · from cache · sorted by publication date

  1. 1
    Role of Oxidative Stress and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 in Nonalcoholic Fatty Liver Disease.

    Memaj P, Ouzerara Z, Jornayvaz FR. · 2023-07-10

    cited 5× open access unreviewed
  2. 2
    A Glimpse into Milestones of Insulin Resistance and an Updated Review of Its Management.

    Aedh AI, Alshahrani MS, Huneif MA, Pryme IF, Oruch R. · 2023-02-12

    cited 16× open access unreviewed
  3. 3
    Therapeutic Drug-Induced Metabolic Reprogramming in Glioblastoma.

    Nguyen TTT, Shang E, Westhoff MA, Karpel-Massler G, Siegelin MD. · 2022-09-22

    cited 23× open access unreviewed
  4. 4
    Non-alcoholic fatty liver disease in type 1 diabetes: Prevalence and pathophysiology.

    Memaj P, Jornayvaz FR. · 2022-12-01

    cited 26× open access unreviewed
  5. 5
    Role of hepatic PKCβ in nutritional regulation of hepatic glycogen synthesis.

    Shu Y, Hassan F, Ostrowski MC, Mehta KD. · 2021-10-08

    cited 3× open access unreviewed
  6. 6
    Advances in Unhealthy Nutrition and Circadian Dysregulation in Pathophysiology of NAFLD.

    Guo X, Zheng J, Zhang S, Jiang X, Chen T, Yu J, Wang S, Ma X, Wu C. · 2021-10-12

    cited 2× open access unreviewed
  7. 7
    Hepatopathy Associated With Type 1 Diabetes: Distinguishing Non-alcoholic Fatty Liver Disease From Glycogenic Hepatopathy.

    Mertens J, De Block C, Spinhoven M, Driessen A, Francque SM, Kwanten WJ. · 2021-10-25

    cited 35× open access unreviewed
  8. 8
  9. 9
    Natural products, an important resource for discovery of multitarget drugs and functional food for regulation of hepatic glucose metabolism.

    Li J, Yu H, Wang S, Wang W, Chen Q, Ma Y, Zhang Y, Wang T. · 2018-01-10

    cited 18× open access unreviewed
  10. 10
    Cats and Carbohydrates: The Carnivore Fantasy?

    Verbrugghe A, Hesta M. · 2017-11-15

    cited 26× open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.