unreviewed
alpha-Galactosidase A (GLA)
1 reactions · 1 pathways
Clinical / pharmacological. Fabry disease (X-linked)
What it does, reaction by reaction
1 reactions
Sphingolipid Degradation (Lysosomal) Lipid Metabolism · Lysosome
step 3
Irreversible/directional
Globotriaosylceramide (Gb3) -> lactosylceramide + galactose
Converts Globotriaosylceramide into Lactosylceramide Galactose
› Notes
X-linked deficiency causes Fabry disease (angiokeratomas, neuropathic pain, renal failure).
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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