What it does, reaction by reaction
Deoxyribonucleotide Formation (Ribonucleotide Reductase pathway and thymidylate synthesis) Nucleotide Metabolism · Cytosol
dTMP → dTDP
› Notes
Thymidylate kinase catalyzes dTMP + ATP → dTDP + ADP. This kinase is specific for thymidylate and is required before dTTP can be generated.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · from cache · sorted by publication date
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1
MTK_MCPA: A novel magnesium-competitive inhibitor of Mycobacterium tuberculosis thymidylate kinase.
Khan MT, Khan HA, Bibi M, Wu H. · 2026-07-17
unreviewed -
2
Integrated comparative genomic and transcriptomic analysis reveals a wsv249 mutation drives enhanced pathogenicity in white spot syndrome virus.
Puttirungroj P, Kawato S, Mwamburi SM, Nozaki R, Naphanang A, Thawonsuwan J, Koiwai K, Kondo H, Hirono I. · 2026-07-04
unreviewed -
3
Integrated quantum chemical and molecular dynamics studies of isoscopoletin against <i>Mycobacterium tuberculosis</i> thymidylate kinase.
Khan HA, Khan MT, Bibi M. · 2026-07-22
unreviewed -
4
Host metabolic responses to SARS-CoV-2 and influenza viruses: parallels and contrasts.
Terra C, Terrier O, Le Gouellec A. · 2026-06-02
open access unreviewed -
5
Targeting Helicobacter pylori thymidylate kinase: structural insights and validation of novel inhibitors.
Kumari K, Khan FM, Bose M, Ls RJ, Yadav A, Mondal N, Gourinath S. · 2026-04-02
unreviewed -
6
Molecular Engineering of Nicotinamide Riboside Kinase and Process Optimization for Efficient Nicotinamide Mononucleotide Production.
Ma D, Liu R, Bao T, Yang J, Zhang H, Hu X. · 2026-05-22
open access unreviewed -
7
Free energy perturbation-derived identification of natural compounds targeting Mycobacterium tuberculosis thymidylate kinase.
Chikhale RV, Islam MA, Suryawanshi VS, Alsarra IA. · 2026-05-26
open access unreviewed -
8
Antimycobacterial Peptides: From Natural Product Discovery to AI Guided Design.
Biswas D, Medina SH. · 2026-04-27
open access unreviewed -
9
Antibiofilm biosynthetic terpene derivatives against clinically and food-relevant bacteria, including synergistic interactions with <b>β</b>-lactam antibiotics: quantum chemical calculations, molecular docking and ADMET study.
Cavalcante RMB, Maria Aguiar Nascimento A, Karyne Rodrigues Muniz R, Híade Silva Cristino J, Moreira de Olive… · 2026-04-20
unreviewed -
10
Silibinin Potentiates Antimicrobial Action and Reduces Staphyloxanthin in <i>Staphylococcus aureus</i>.
Pereira-Filho JL, Mendes AGG, Campos CDL, Almeida VDSS, Pereira APA, Moreira IV, Monteiro CRAV, Gomes LN, Rho… · 2026-04-18
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.