What it does, reaction by reaction
Deoxyribonucleotide Formation (Ribonucleotide Reductase pathway and thymidylate synthesis) Nucleotide Metabolism · Cytosol
dTMP → dTDP
› Notes
Thymidylate kinase catalyzes dTMP + ATP → dTDP + ADP. This kinase is specific for thymidylate and is required before dTTP can be generated.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · from cache · sorted by publication date
-
1
MTK_MCPA: A novel magnesium-competitive inhibitor of Mycobacterium tuberculosis thymidylate kinase.
Khan MT, Khan HA, Bibi M, Wu H. · 2026-07-17
unreviewed -
2
Nuclear proteome analysis suggests spatial and temporal compartmentalization of metabolic enzymes during Trypanosoma cruzi cell cycle.
Menezes AP, Gachet-Castro C, McGill S, Burchmore R, Silber A, Elias MC, da Cunha JPC. · 2026-09-28
open access unreviewed -
3
Bioprospecting Chromobacterium violaceum for bioremediation: an alternative to environmental lead pollution.
de Alencar FLS, Navoni JA, de Lima DC, Brant RSC, do Amaral VS. · 2026-09-04
open access unreviewed -
4
Genomic characterization and therapeutic potential of five broad-spectrum lytic bacteriophages against multidrug-resistant avian pathogenic <i>Escherichia coli</i> (APEC).
Midha T, Vishakha, Baranwal S. · 2026-07-20
open access unreviewed -
5
Structural Modifications of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): New Horizons in Antimicrobial Drug Discovery.
Koçak Aslan E, Karagüzel A, Gündüz MG. · 2026-08-01
open access unreviewed -
6
Viral inhibition of the anaphase promoting complex enhances replication by elevating nucleotide pools.
Chen OJ, Feng CY, Blanchette P, Ladak RJ, Crosby MA, de Sá Tavares Russo M, Wang Y, Fernandez C, Liang Y, Sha… · 2026-08-12
open access unreviewed -
7
Piperazine linked chitosan schiff base nanoparticles as a novel antibiofilm and antibacterial strategy against clinically relevant pathogens.
Soliman MM, Bayoumy AE, Hamed AA, Gabre RM, Abd-Elhakeem MA, Abdelhamid IA, Elgamal AM. · 2026-08-06
open access unreviewed -
8
Exploring drug repurposing for monkeypox virus: A structural and computational approach.
Gul S, Akhtar F, Rehman I, Shah M, Rashid U, Rauf A. · 2026-06-25
open access unreviewed -
9
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite.
Xu Y, Liclican A, Zhao X, Chen C, Ortega JT, Chuang H-C, Soulette C, Chaudhuri S, Zhang J, Wang T, Babusis D,… · 2026-06-22
open access unreviewed -
10
Improving hit discovery by integrating activity cliff sensitivity into active learning.
Kim J, Kim Y, Koo B, Bang D, Kim S. · 2026-07-01
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.