What it does, reaction by reaction
Cholesterol Biosynthesis (Mevalonate Pathway) Lipid Metabolism · Cytosol + ER
5-Phosphomevalonate + ATP → 5-pyrophosphomevalonate + ADP
Converts 5-Phosphomevalonate ATP into 5-Pyrophosphomevalonate ADP
› Notes
Phosphomevalonate kinase adds a second phosphate using ATP.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
<i>De novo</i> production of (-)-limonene, (-)-carveol and (-)-carvone via engineering <i>Rhodotorula toruloides</i>.
Dong Y, Cui S, Du B, Zhang X, Hou J, Lin X, Qin Y, Wang X, Yang X. · 2026-06-13
open access unreviewed -
2
Active ROP2 triggers leaf senescence and orchestrates the growth-senescence trade-off under nitrogen starvation.
Zhang T, Ye H, Zhang Y, Wang J, Wang J, Lixiang S, Lin Z, Xiong Y, Liu Y. · 2026-06-13
open access unreviewed -
3
Shikimate crosstalk enables record-level homogentisic acid production in <i>Yarrowia lipolytica</i>.
Xu C, Zhang W, Zhao Q, Lin X, Wang K, Wang M, Tan T. · 2026-04-15
open access unreviewed -
4
Synergistic engineering of monoterpenoid synthase and metabolic pathways to enhance α-terpineol production in <i>Saccharomyces cerevisiae</i>.
Wang S, Wang X, Wang Y, Li C. · 2026-04-10
open access unreviewed -
5
Mitotic error correction and the spindle assembly checkpoint: a tension-filled relationship.
Pleuger R, Westermann S. · 2026-04-03
open access unreviewed -
6
Molecular mechanisms of folliculogenesis and oogenesis.
Ezz MA, Balboula AZ. · 2026-04-02
cited 1× open access unreviewed -
7
The TRAP complex (SSR1-SSR4): mechanistic roles and therapeutic opportunities.
Zhang J, Wan X, Gong A. · 2026-02-06
open access unreviewed -
8
Deciphering the PgLEA2-50 interactome: implications for abiotic stress responses in <i><b>Panax ginseng</b></i>.
Wang Q, Liu J, Zhang M, Wang P, Li T, Bian X, Chen X, Chen S, Wang L, Lei J, Han L, Xu M, Zhang Q, Lei X, Wan… · 2026-02-05
open access unreviewed -
9
Autophagy targeted nano-medicine in norphytane atrophic arthritis model: Beclin1/XBP/PTEN/STAT-3A genetic profile.
O Kadry M, Abdel-Megeed RM. · 2026-01-12
open access unreviewed -
10
Kinetochore clustering is mediated by Mps1 phosphorylation of conserved MELT motifs in Stu1.
Mallett DR, Jiang M, Minnuto GM, Biggins S. · 2026-07-16
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.