What it does, reaction by reaction
Cholesterol Biosynthesis (Mevalonate Pathway) Lipid Metabolism · Cytosol + ER
5-Phosphomevalonate + ATP → 5-pyrophosphomevalonate + ADP
Converts 5-Phosphomevalonate ATP into 5-Pyrophosphomevalonate ADP
› Notes
Phosphomevalonate kinase adds a second phosphate using ATP.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Aurora kinase a phosphorylates and stabilizes UHRF1 to maintain DNA methylation and prostate cancer cell survival.
Xiang Q, Peng Y, Ye Y, Li X. · 2026-09-25
open access unreviewed -
2
Menaquinone biosynthesis in <i>Lactococcus lactis</i>: Recent advances and future prospects.
Lou Y, Shuang J, Kong J, Guo T. · 2026-09-02
open access unreviewed -
3
Citron Kinase, a mitotic kinase with increasing significance in cancer.
Mitri E, Callot C, Hatzoglou A, Besson A. · 2026-09-13
open access unreviewed -
4
Non-ergosterol lipid remodeling governs amphotericin B susceptibility via TOR-calcineurin signaling in <i>Candida glabrata</i>.
Kumar M, Kumari S, Wasi M, Ali B, Kumar P, Sharma G, Singh A, da Silva Dantas A, Gow NAR, Gaur NA, Prasad R. · 2026-08-26
open access unreviewed -
5
Porcine deltacoronavirus nucleocapsid protein inhibits RIG-I signaling pathway by suppressing G3BP1-mediated stress granules formation.
Guo M, Hu Y, Wang D, Tang Y, Yuan J, Shi C, Zu S, Wei Z. · 2026-08-23
open access unreviewed -
6
Practical management of BRAF inhibitors in glioma: toxicity and resistance.
Bazer D, Ayanlaja AA, Schreck KC. · 2026-08-03
open access unreviewed -
7
The Mediator complex: co-transcriptional regulation and beyond.
Yang Y, Zheng Y, Zhou Q, Wang G. · 2026-07-28
open access unreviewed -
8
Branched-chain amino acids and gut microbiota: coregulation and impact on neurological function via the gut-brain axis.
Li Q, Fan B, Xiao Y, Zhang Z, Zhao S, Liao B, Zeng J, Shan X, Ye H, Wen Y, Zhang L, Guo H, Xiao F, Zhu H. · 2026-07-14
open access unreviewed -
9
Integrated metabolomic and transcriptomic analysis reveal the flavor formation mechanism during oat grain development.
Qin Y, Wang T, Liu H, Guo Y, Yang X, Yang Y, Shagdarsuren D, Han B. · 2026-06-22
open access unreviewed -
10
Calcium overload-induced apoptosis in cancer cells: ER-mitochondria crosstalk and therapeutic implications.
Ding Y, Liu X, Xue J, Fu J, Liu S, Xu X, Jiao X, Wu Z, Yang G, Wang H, Zhang P. · 2026-06-22
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.