Phospholipase A2
Cofactors used
Clinical / pharmacological. Suppressed indirectly by corticosteroids (annexin/lipocortin)
What it does, reaction by reaction
Eicosanoid Synthesis Lipid Metabolism · Cytosol / ER / nuclear membrane
Membrane phospholipid -> arachidonic acid + lysophospholipid
Converts Phospholipid into Arachidonic acid Lysophospholipid
› Notes
Rate-limiting release of the 20:4 omega-6 precursor. Corticosteroids suppress this step.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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