Phosphoglucomutase
What it does, reaction by reaction
Galactose Metabolism Carbohydrate Metabolism · Cytosol
Glucose-1-phosphate ↔ glucose-6-phosphate
Converts Glucose-1-phosphate into Glucose-6-phosphate
› Notes
Phosphoglucomutase reversibly forms glucose-6-phosphate through a glucose-1,6-bisphosphate intermediate. The product can enter glycolysis, glycogenesis, or, in liver, be converted to free glucose by glucose-6-phosphatase.
Glycogenesis (Glycogen Synthesis) Carbohydrate Metabolism · Cytosol (glycogen particle)
Glucose-6-phosphate ↔ glucose-1-phosphate
Converts Glucose-6-phosphate into Glucose-1-phosphate
› Notes
Phosphoglucomutase reversibly transfers the phosphate through a glucose-1,6-bisphosphate intermediate; a catalytic phosphoserine is primed by glucose-1,6-bisphosphate. This reaction directs glucose carbon toward activated-sugar formation.
Glycogenolysis (Glycogen Breakdown) Carbohydrate Metabolism · Cytosol + ER (liver)
Glucose-1-phosphate ↔ glucose-6-phosphate
Converts Glucose-1-phosphate into Glucose-6-phosphate
› Notes
Cytosolic phosphoglucomutase reversibly transfers the phosphate via glucose-1,6-bisphosphate. In muscle, glucose-6-phosphate enters glycolysis; in liver it is prepared for export.
Showing all 3 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Impact of leucine-rich diet on placenta's proteomic and metabolomic profiles of pregnant tumor-bearing rats.
Dos Santos IF, Salgado CM, Carregari VC, Dos Santos RW, de Souza DM, Viana LR, Gomes-Marcondes MCC. · 2026-05-14
open access unreviewed -
2
Efficient whole-cell biotransformation for gastrodin production via glycosyltransferase engineering and process optimization.
Wang X, Zhang J, Li T, Wang F, Wang Z, Li X. · 2026-04-06
open access unreviewed -
3
Stepwise phage resistance and collateral phage susceptibility in <i>Klebsiella pneumoniae</i>.
Yin X, Feng Y, Luo H, Fang Q, Yu J, McNally A, Zong Z. · 2026-05-29
cited 1× open access unreviewed -
4
An update on regulation of the polymodal TRPV4 channel by protein phosphorylation.
Parthasarathy A, Zhang DX. · 2026-01-19
open access unreviewed -
5
Small regulatory RNAs mediated regulation of virulence and host-pathogen interaction in the Gram-negative ESKAPE pathogens.
Li L, Zhang Z, Zhu H, Cui K, Song X, Wang Z, Chen L, Yu Z, Zhang W, Sun H, Yu Z, Duan Y, Li M. · 2025-12-18
open access unreviewed -
6
High-level biosynthesis of gastrodin in engineered Escherichia coli.
Ge L, Jia R, Xu W, Xia Y, Pei J. · 2026-06-27
unreviewed -
7
Structure-coevolution dual-guided engineering of C-glycosyltransferase enables high-level biosynthesis of vitexin in <i>Yarrowia lipolytica</i>.
Shi CQ, Chen YJ, Yang WL, Zheng S, Cai R, Hou J, Wang DQ, Sheng JZ. · 2026-03-09
open access unreviewed -
8
Enzyme promiscuity-driven co-production of flavonoid 7-<i>O</i>-glycosides in engineered <i>Saccharomyces cerevisiae</i>.
Tan X, Zuo S, Hu F, Xiao Z, Wang Y, Zhang S, Lu Q, Zhao Y, Chen J, Fan L, Liu J, Shan Y. · 2026-02-12
cited 1× open access unreviewed -
9
Construction of a globally modular recombinant <i>Saccharomyces cerevisiae</i> chassis for ginkgolide precursor levopimaradiene production.
Liu, Chen Z, Guo Z, Xue Q, He Q, Yu R, Zhu J. · 2026-02-05
open access unreviewed -
10
The MagMa Study: Quantum Magnetocardiography in Cardiomyopathy.
Suwalski P, Wilke F, Latinova E, Paci G, Satilmis G, Klingel K, Kelle S, Weiner J, Beule D, Lüscher TF, Landm… · 2026-08-01
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.