Non-enzymatic (spontaneous decarboxylation)
What it does, reaction by reaction
Ketogenesis Lipid Metabolism · Liver mitochondrial matrix
Acetoacetate → acetone + CO2
Converts Acetoacetate into Acetone CO2
› Notes
Acetoacetate undergoes slow, largely spontaneous nonenzymatic decarboxylation to acetone in humans; acetone is volatile and exhaled. This is not a productive ATP-generating step and is not a regulated enzymatic reaction.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Efficient (S)-acetoin production in Saccharomyces cerevisiae by modulating α-acetolactate decarboxylase stereospecificity
Cha S, Jang B, Lee D, Cho I, Park W, Lee Y, Shin H, Kim M, Sung C, Hahn JS. · 2025-10-01
unreviewed -
2
Efficient (S)-acetoin production in Saccharomyces cerevisiae by modulating α-acetolactate decarboxylase stereospecificity.
Cha S, Jang B, Lee D, Cho I, Park W, Lee Y, Shin H, Kim M, Sung C, Hahn JS. · 2025-06-03
cited 2× unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.