unreviewed
Monoacylglycerol acyltransferase + DGAT + ACAT2 (enterocyte)
1 reactions · 1 pathways
What it does, reaction by reaction
1 reactions
Lipoprotein Metabolism (Exogenous and Endogenous Pathways: chylomicrons, VLDL, LDL, HDL) Lipid Metabolism · Intestine, liver, plasma, capillary endothelium
step 2
Irreversible/directional
Fatty acids/monoacylglycerol + enterocyte re-esterification → TAG; cholesterol → cholesteryl ester
into Triacylglycerol (TAG) Cholesterol
› Notes
Enterocytes re-form TAG mainly through the monoacylglycerol pathway (monoacylglycerol acyltransferase and DGAT) and esterify cholesterol through acyl-CoA:cholesterol acyltransferase 2 (ACAT2). These reactions use activated fatty acyl-CoA; long-chain lipids are assembled for export.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
No articles returned.