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MS
unreviewed

Mevalonate kinase

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Cholesterol Biosynthesis (Mevalonate Pathway) Lipid Metabolism · Cytosol + ER

step 4 Irreversible/directional

Mevalonate + ATP → 5-phosphomevalonate + ADP

Converts Mevalonate ATP into 5-Phosphomevalonate ADP

Notes

Mevalonate kinase phosphorylates the C5 hydroxyl group. ATP is required.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · fetched just now · sorted by publication date

  1. 1
    <i>De novo</i> production of (-)-limonene, (-)-carveol and (-)-carvone via engineering <i>Rhodotorula toruloides</i>.

    Dong Y, Cui S, Du B, Zhang X, Hou J, Lin X, Qin Y, Wang X, Yang X. · 2026-06-13

    open access unreviewed
  2. 2
    Shikimate crosstalk enables record-level homogentisic acid production in <i>Yarrowia lipolytica</i>.

    Xu C, Zhang W, Zhao Q, Lin X, Wang K, Wang M, Tan T. · 2026-04-15

    open access unreviewed
  3. 3
  4. 4
    Molecular mechanisms of folliculogenesis and oogenesis.

    Ezz MA, Balboula AZ. · 2026-04-02

    cited 1× open access unreviewed
  5. 5
  6. 6
    Synergy between varied Pd sites on CeO<sub>2</sub> for enhanced low-temperature passive NO<sub>x</sub> adsorption.

    Li X, Zhang H, Gao M, Gao Z, Mei Y, Liu Y, Zhong W, Chen A, Zhang D. · 2026-04-19

    unreviewed
  7. 7
    Metabolic and transport engineering enable efficient de novo biosynthesis of patchoulol in <i>Saccharomyces cerevisiae</i>.

    Fu D, Zhou Y, Wu Z, Wang S, Lao Y, Wang HB, Jin HL. · 2026-02-09

    cited 1× open access unreviewed
  8. 8
    Metabolic engineering of endogenous MEP pathway for enhanced lycopene production in <i>Escherichia coli</i>.

    Xu X, Xing H, Zhi H, Qin C, Deng Y, Wei W, Huang C. · 2026-01-30

    open access unreviewed
  9. 9
    Targeted identification of new phaterpenes and elucidation of the relevant biosynthetic pathway in <i>Streptomyces phaeochromogenes</i> OSK-123.

    Fan X, Zhang X, Tang M, Wei S, Guo Z, Ren F, Hao J, Hua L, Zhou L, Xu J, Huang W, Kang Q, Bai L. · 2026-01-25

    open access unreviewed
  10. 10

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.