Skip to content
MS
unreviewed

Maleylacetoacetate isomerase

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Amino Acid Catabolism Overview (glucogenic vs. ketogenic amino acids; brief overview of branched-chain amino acid catabolism and phenylalanine/tyrosine catabolism as representative examples) Amino Acid & Nitrogen Metabolism · Cytosol + mitochondrion

step 13 Irreversible/directional

Maleylacetoacetate → fumarylacetoacetate

Converts Maleylacetoacetate into Fumarylacetoacetate

› Notes

Maleylacetoacetate isomerase uses glutathione as a cofactor. The isomerization prepares the molecule for hydrolytic cleavage.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · fetched just now · sorted by publication date

  1. 1
    Phase III trial of sodium dichloroacetate for pyruvate dehydrogenase complex deficiency in children.

    Stacpoole PW, Abdenur JE, Bedoyan JK, Botto L, Enns GM, Falk MJ, Ganetzky R, Garganta C, Glinton K, Gropman A… · 2026-09-22

    open access unreviewed
  2. 2
    The Spanish Uniform Newborn Screening Panel (SUSP): A National Consensus Framework for Harmonized Newborn Screening.

    García-Villoria J, López-Galera RM, Delgado-Pecellín C, Rausell Félix D, Colón C, Rocha H, Pérez B, Ribes A, … · 2026-08-13

    open access unreviewed
  3. 3
  4. 4
    GSH-Related Enzymes GPx4, Chac1, and GSTs and Redox Regulation of Ferroptosis in Cancer.

    Kalinina E. · 2026-07-17

    cited 1× open access unreviewed
  5. 5
    Transcriptomic responses of red palm weevil (Coleoptera: Curculionidae) larvae to low-temperature exposure.

    Antón-Ruiz N, Larriba E, León-Quinto T, Serna A, Pérez-Pérez JM. · 2026-07-01

    open access unreviewed
  6. 6
    Transcriptomic analyses of labial glands and gut tissue from two wax moths, Achroia grisella and Galleria mellonella.

    Young R, Ahmed KA, Court L, Rane R, Walsh T, Pandey G. · 2026-07-01

    open access unreviewed
  7. 7
    Targeting GSTZ1 Sensitizes KRASG12C-Mutant Lung Cancer Cells by Overcoming Glutathione and Glycolysis Pathway Rewiring.

    Liao Y, Li X, Liu M, Fernandes VC, Duckett D, Haura EB, Monastyrskyi A, Rix U. · 2026-06-01

    open access unreviewed
  8. 8
    Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria.

    Rutland DA, Norman BP, Hughes JH, Wilson PJM, Sutherland H, Brown RLW, Gallagher JA, Ranganath LR, Bou-Ghario… · 2026-05-01

    open access unreviewed
  9. 9
    Bacillus velezensis EU07 suppresses Fusarium graminearum via transcriptomic reprogramming.

    Baysal Ö, Jimenez-Quiros C, Cevher-Keskin B, Tör M. · 2026-05-08

    open access unreviewed
  10. 10
    Genomic and functional insights into aromatic compound degradation by <i>Delftia</i> strain PS-11 isolated from freshwater pufferfish.

    Archana Kujur RR, Deb S, Debnath T, Papade S, Phale PS, Das SK. · 2026-04-01

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.