Lipoprotein lipase (LPL) + hepatic lipase
Clinical / pharmacological. LPL or apoC-II deficiency: familial chylomicronaemia (type I), pancreatitis
What it does, reaction by reaction
Lipoprotein Metabolism (Exogenous and Endogenous Pathways: chylomicrons, VLDL, LDL, HDL) Lipid Metabolism · Intestine, liver, plasma, capillary endothelium
Chylomicron → chylomicron remnant
Converts Chylomicron into Chylomicron remnant
› Notes
Continued LPL-mediated TAG removal returns apoC-II to HDL and produces a cholesterol-enriched, apoB-48/apoE-containing remnant. Hepatic lipase can further remodel remnants. This stage does not designate one single enzyme but is a sequence of intravascular lipolysis and apolipoprotein exchange.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Predicting longevity-related traits in Swiss low-input and organic dairy cows from herdbook data of first versus second lactation.
Bieber A, Hinrichs D, Moser FN, Maeschli A, Lora I, Cozzi G, Leiber F. · 2026-05-19
unreviewed -
2
Effects of dietary nano-selenium and lysophospholipid supplementation on sperm quality and testicular histomorphometry in Moghani ram.
Aghazadeh L, Mirzaei Aghjeh-Gheshlagh F, Jahani-Azizabadi H, Navid-Shad B, Kalantari-Hesari A, Staji H. · 2026-06-11
unreviewed -
3
The RNA binding protein ZFP36L2 displays tissue-selective mRNA targeting in mice.
Stephenson GS, Fleifel D, Cook JG, Laederach A, Ramos SBV. · 2026-06-21
open access unreviewed -
4
Multi-omics integration reveals convergent extracellular matrix remodelling and lipid metabolic reprogramming as central axes of adipocyte differentiation from mouse embryonic stem cells.
Al-Sayegh M, Khalili M, Alzaabi M, Sultana M, Ali L, Ali M, El-Hadidi M. · 2026-06-02
open access unreviewed -
5
Combining bioinformatics and machine learning to analyze and validate sepsis-related cell senescence genes and potential drugs.
Pei S, Li D, Yu X, Huang X, Liu J, Song Y, Zhu L, Cui J, Cui Y, Xie K. · 2026-05-31
open access unreviewed -
6
Magnetic nanohydroxyapatite-peptide silk fibroin hydrogel induces osteogenesis in canine periodontal ligament stem cells revealed by proteomic analysis.
Purbantoro SD, Scatena M, Taephatthanasagon T, Rodprasert W, Somparn P, Nanthawong S, Makjaroen J, Jantaratan… · 2026-05-16
open access unreviewed -
7
Triglyceride deposit cardiomyovasculopathy as a predictor of vascular failure after coronary intervention in patients with hemodialysis: a preliminary analysis.
Fujimoto M, Nakano Y, Hirano KI, Onishi T, Ando H, Ohashi H, Satake A, Waseda K, Takahashi H, Amano T. · 2026-04-22
open access unreviewed -
8
<i>Valeriana</i> species and insomnia: multi-organ mechanisms and translational perspectives.
Yang S, Zhang H, Chen L, Zhang Z, Huang L, Wang W, Lu W, Wang Y, Wu S, Hu Z, Wang S, Chen R, Liang F. · 2026-04-17
open access unreviewed -
9
The Crimean-Congo haemorrhagic fever virus hijacks the liver lipid metabolic pathway for virion production.
Gautam A, Zhong L, Ogire E, Bodoirat S, Riedmiller I, Sander WJ, Boson B, Gandhi A, Burlaud-Gaillard J, Amira… · 2026-03-30
open access unreviewed -
10
Dysregulated eating behaviour and microbiota-based interventions targeting eating disorders and food addiction.
Samulėnaitė S, Rodriguez Parkitna J, Baltriukienė D, Martín-García E, Maldonado R, Burokas A. · 2026-03-29
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.