Lipoprotein lipase (LPL) + hepatic lipase
Clinical / pharmacological. LPL or apoC-II deficiency: familial chylomicronaemia (type I), pancreatitis
What it does, reaction by reaction
Lipoprotein Metabolism (Exogenous and Endogenous Pathways: chylomicrons, VLDL, LDL, HDL) Lipid Metabolism · Intestine, liver, plasma, capillary endothelium
Chylomicron → chylomicron remnant
Converts Chylomicron into Chylomicron remnant
› Notes
Continued LPL-mediated TAG removal returns apoC-II to HDL and produces a cholesterol-enriched, apoB-48/apoE-containing remnant. Hepatic lipase can further remodel remnants. This stage does not designate one single enzyme but is a sequence of intravascular lipolysis and apolipoprotein exchange.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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