Isopentenyl pyrophosphate isomerase
What it does, reaction by reaction
Cholesterol Biosynthesis (Mevalonate Pathway) Lipid Metabolism · Cytosol + ER
IPP ⇌ dimethylallyl pyrophosphate (DMAPP)
Converts Isopentenyl pyrophosphate (IPP) into Dimethylallyl pyrophosphate (DMAPP)
› Notes
Isopentenyl pyrophosphate isomerase rearranges IPP to the allylic isomer DMAPP. No net ATP or NADPH is required.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Biological-chemical method for synthesizing <i>p</i>-menthane-3,8-diol.
Zuo X, Zhang H, Zhang Z, Ma Y, Zhang C, Lu W. · 2026-05-12
open access unreviewed -
2
Constructing an efficient synthesis pathway in peroxisomes to boost <i>β</i>-myrcene production in yeast.
Chang J, Wang J, Dong T, Shu Y, Wang Y, Xiao W, Yao M, Yuan Y. · 2026-04-25
open access unreviewed -
3
8-Chloroadenosine suppresses hepatocellular carcinoma progression via ADAR1/PPARγ axis-mediated lipid metabolism.
Liu J, Zhao Y, Gong X, Yuan L, Yang S, Jian W, Yan H, Chen H, Yang Z, Sun Y, Gu T, Lu H, Zhao H, Tu Z. · 2025-09-26
open access unreviewed -
4
Systematic engineering to enhance 3-carene production in yeast.
Wu F, Dong T, Gao Q, Wang H, Shan M, Guan L, Wang Y, Xiao W, Yao M. · 2026-04-24
open access unreviewed -
5
Metabolic and transport engineering enable efficient de novo biosynthesis of patchoulol in <i>Saccharomyces cerevisiae</i>.
Fu D, Zhou Y, Wu Z, Wang S, Lao Y, Wang HB, Jin HL. · 2026-02-09
cited 1× open access unreviewed -
6
Construction of a globally modular recombinant <i>Saccharomyces cerevisiae</i> chassis for ginkgolide precursor levopimaradiene production.
Liu, Chen Z, Guo Z, Xue Q, He Q, Yu R, Zhu J. · 2026-02-05
open access unreviewed -
7
Metabolic engineering of endogenous MEP pathway for enhanced lycopene production in <i>Escherichia coli</i>.
Xu X, Xing H, Zhi H, Qin C, Deng Y, Wei W, Huang C. · 2026-01-30
open access unreviewed -
8
The R2R3-MYB transcription factor ApMYB9 links UV-B signaling to andrographolide biosynthesis by activating ApIPPI in Andrographis paniculata.
Li J, Xu S, Sun M, Gu Y, Wang J. · 2026-06-27
unreviewed -
9
Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review).
Liu Q, Wang R, Li Z, Liu Y, Wu L, Zhao Y, Yang J. · 2026-06-05
open access unreviewed -
10
Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1.
Xiao L, Li L, Wu S, Che Z, Du Y, Zheng J, Yan J, Wang H, Zhang H, Li Y, Xiao J. · 2026-07-28
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.