Histidine decarboxylase (HDC)
Cofactors used
What it does, reaction by reaction
Other Neurotransmitter Synthesis Amino Acid & Nitrogen Metabolism · Cytosol
L-Histidine -> histamine + CO2
Converts Histidine into Histamine CO2
› Notes
Stored in mast cells and basophils; degraded by diamine oxidase and histamine N-methyltransferase.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Colonic nutritional and physicochemical parameters drive gut microbiota dysbiosis in obesity: what we learned from the Ob-M-ARCOL model development.
Uriot O, Deschamps C, Etienne-Mesmin L, Brun M, Pouget M, Chalancon S, Durif C, Chaudemanche C, Alric M, Boir… · 2026-06-09
open access unreviewed -
2
CRISPR/Cas9 mediates precise and efficient gene editing in <i>Xanthomonas oryzae</i> pv. <i>oryzae</i>.
Luo Y, Sun S, Xi JJ. · 2026-04-27
open access unreviewed -
3
Integrating bulk and single-cell transcriptomic data to construct a risk model for histidine metabolism-related epithelial cell features in lung adenocarcinoma, predicting prognosis and immune landscape.
Mao C, Zhou L. · 2026-04-28
open access unreviewed -
4
Aging-caused the changes of the gut microbiota drive intestinal barrier dysfunction and increase sepsis susceptibility.
Liang H, Ding X, Liu S, Tong S, Wang X, Zhang Z, Wang W, Zhang X, Yuan Y, Jiang Y, Sun T. · 2026-02-21
open access unreviewed -
5
Integrated smartphone-sensing and remediation platform empowered by hole-confinement-triggered Fe-Cu diatomic nanozymes for precise management of tetracyclines.
Niu X, Wang X, Huo N, Wang H. · 2026-06-28
unreviewed -
6
Proteasome Inhibitor-Induced Cytotoxic Mechanisms in Canine Pulmonary Adenocarcinoma Cell Lines.
Chijiwa A, Inanaga S, Osaki T, Igase M, Mizuno T. · 2026-04-06
unreviewed -
7
Supplementation of a DHA commercial lipid emulsion in diets for tropical gar (Atractosteus tropicus) larvae: effects on growth, cannibalistic behavior, digestive enzyme activity, and aggressiveness-related genes.
Sepúlveda-Quiroz CA, Alvarez-Villagomez CS, Jiménez-Martínez LD, Peña-Marín ES, Mendoza-Porras O, Pérez-Jimén… · 2026-08-08
unreviewed -
8
A multi-institutional report of children with atypical teratoid rhabdoid tumor treated with intensive multimodal therapy.
Margol AS, Hoffman LM, Ronsley R, Tran J, Malvar J, Chi YY, Leary S, Stevens J, Faulk KE, Salloum R, Hutchins… · 2026-02-19
unreviewed -
9
Developmental Progress and Future Potential for Inhaled Biologics in the Treatment of Respiratory Diseases.
Giri BR, Spahn JE, Alsaidalani R, Behrend-Keim B, Bhia M, Doyle JH, Herpin MJ, Moore RC, Murali NS, Safak A, … · 2026-06-20
unreviewed -
10
The role of histidine metabolism in tumor progression and its clinical significance.
Zhang Y, Lin R, Wang Y, Dong J, Liang F. · 2026-06-09
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.